RESUMO
Objective: To determine the effects of George Ohsawa One [GO1] on sodium, potassium, calcium, hemoglobin and platelet count in rabbits with and without anticoagulated blood
Study Design: Interventional study
Place and Duration of Study: This study was conducted at the Department of Pharmacology, FederalPost Graduate Medical Institute and National Health Research Complex, PMRC, Sheikh Zayed Hospital Complex, Lahore from January 2010 to August2011
Materials and Methods: Forty eight [n=48] male rabbits were included in the study. They were divided into two groups which were further divided into two subgroups each. About 700 grams of GO1 was used in the study
Results: The effect of GO1 on platelet count, hemoglobin, serum sodium, potassium and calcium were found to be insignificant
Conclusion: This work on the effect of GOI is first of its kind on biochemical and hematological parameters other than prothrombin time and activated partial thromboplastin time in rabbits measured quantitatively. Although theuse of herbal products may not be dangerous per se, further research work is required to explore the benefits of GO1 on biochemical and hematological parameters before it can safely be used in humans as an anti-hemorrhagic agent