comparison of oral ivermectin and topical lindane in the treatment of scabies

Scabies is a common skin disease and a public health problem. The topical antiscabietics have a poor compliance. The aim of this study was to compare the efficacy of oral Ivermectin with topical Lindane solution in the treatment of scabies. This was a prospective comparative open study. Fifty seven patients were randomized in two groups. One group [32 patients] received 200mg/kg body weight of Ivermectin in two oral doses with a one-week interval, and the second group, [25 patients] received 2 consecutive weekly topical applications of Lindane. All patients were followed up for 2 weeks. A single oral dose of Ivermectin cured 72% of patients and 91% of the patients were cured after the second dose. Two applications of Lindane with a one-week interval cured 92% of cases. Compared to topical Lindane in the treatment of scabies, Ivermectin was at least as effective as Lindane

Pseudoxanthoma elasticum: a report of three cases in a family

Pseudoxanthoma Elasticum is an inherited disorder characterized by generalized fragmentation and progressive calcification of the elastic tissues in the dermis, blood vessels and Bruch's membrane of the eye. Herein, we report 3 patients in a family with pseudoxanthoma elasticum: a father and his two sons

Lepromatous leprosy presenting with lichenoid papules

A 45-year Iranian man referred to the clinic with a severe itching and multiple papular lesions on his trunk, buttocks and extremities. Symptoms and signs of lesions simulated the clinical features of mycosis fungoides [Cutaneous T cell lymphoma]. There were [not any] no typical features of leprosy except a localized patch of numbness on the right hand. Slit skin smear and histopathological slide showed features of lepromatous leprosy. Clinicians practicing in leprosy endemic areas should keep lepromatous leprosy in mind while investigating patients with varied and multiple lesions