Clinical study on role of CECT abdomen in intestinal obstruction

Background: Intestinal obstruction is a common clinical occurrence and can be either dynamic or adynamic. The old saying “Never let the sun set or rise on an obstructed bowel” taught to minimize missing strangulation. Helical CT with its multiplanar reformatted imaging can accurately characterize the level, degree, cause and associated complications of obstruction. Aim of the study was to depict the spectrum of MDCT findings in cases of small and large bowel obstruction and correlation of CT scan with intraoperative findings and the cause of intestinal obstruction.Methods: Contrast enhanced MDCT examination of 50 patients were prospectively included in the study who had evidence of clinical as well as MDCT evidence of bowel obstruction and in whom surgical/clinical follow-up for final diagnosis was available. CT scan was done in all the patients with MDCT (Brightspeed GE 16 slice system). The axial sections were reconstructed in coronal and saggital planes to determine site and cause of bowel obstruction.Results: The commonest cause of intestinal obstruction in adults in this study series was adhesions/bands in 38% cases. Out of 47 operated patients for intestinal obstruction, CT findings matched with intraoperative findings in 43 patients (91%) whereas cause of intestinal obstruction matched with CT findings in 37 patients (74%).Conclusions: Management decisions in intestinal obstruction remain notoriously difficult, relying on a combination of clinical, laboratory, and imaging factors to help stratify patients into conservative or surgical treatment. CT in these patients can help surgeon to go for surgery early and prevent complications.

Predictive value in computed tomography in diagnosing stage of renal tumors

Objective: To determine the frequency of true positive cases in staging of renal cell carcinoma on computed tomography[CT] tacking histopathology as gold standard

Methods: 75 patients diagnosed as RCC on CT underwent nepherectomies and histopathological / radiological staging were compared

Results: The overall sensitivity of CT for diagnosing RCC was 93.33%. For T1a 100%, for T1b 51.7%, for T2 80%, for T3a 75%, for T3b 2% and for T4 100%. The sensitivity for N1 and N2 is 66.67% and 80.2% respectively. CTshowed higher stage in 43.3% cases

Conclusion: Computed tomography is still a good diagnostic modality for pre-operative staging of RCC and planning of surgery

Ilaj-bil-Riyazat a way of natural cure

The Haj-Bit-Tadbeer [Regimenal Therapy] of Unani System of Medicine is a unique way of treatment, in which ailments are cured without or with least use of drugs. The basic concept of llaj-bit-tadbeer is based upon the Theory of Tabiyat, which is the ultimate curator and it may prove pivotal in achieving the goal of GLOBAL HEALTH in community perspective. According to O.C. Gruner, the authority on Basics of Medicines, [It [Tabiyat] would aim at reasons for health and ill health far deeper than those given by microbic and cognate theory]. Riyazat [Exercise] is a method of treatment of Regimenal Therapy which is used as a tool to keep the body fit and sound and also help to treat various diseases, especially those diseases which are caused by such humours that can be liquefied and then mobilized to elimination by Innate Heat. Riyazat helps to boost the innate heat, a tool of Tabiyat, which then overcome disease causing matter, and thus help in treatment of diseases like - Osteo-arthritis, Obesity, Cervical Spondylitis, Cardiovascular disorders etc

Changes in synapses and axons demonstrated by synaptophysin immunohistochemistry following spinal cord compression trauma in the rat and mouse / 生物医学与环境科学（英文）

<p><b>OBJECTIVE AND METHODS</b>To evaluate synaptic changes using synaptophysin immunohistochemstry in rat and mouse, which spinal cords were subjected to graded compression trauma at the level of Th8-9.</p><p><b>RESULTS</b>Normal animals showed numerous fine dots of synaptophysin immunoreactivity in the gray matter. An increase in synaptophysin immunoreactivity was observed in the neuropil and synapses at the surface of motor neurons of the anterior horns in the Th8-9 segments lost immunoreactivity at 4-hour point after trauma. The immunoreactive synapses reappeared around motor neurons at 9-day point. Unexpected accumulation of synaptophysin immunoreactivity occurred in injured axons of the white matter of the compressed spinal cord.</p><p><b>CONCLUSION</b>Synaptic changes were important components of secondary injuries in spinal cord trauma. Loss of synapses on motor neurons may be one of the factors causing motor dysfunction of hind limbs and formation of new synapses may play an important role in recovery of motor function. Synaptophysin immunohistochemistry is also a good tool for studies of axonal swellings in spinal cord injuries.</p>