RESUMO
Objectives: To evaluate the prevalence of metabolic syndrome in patients with psoriasis in Yazd, Iran
Design: A cross sectional study conducted among Iranian patients with psoriasis and age and sex - matched controls
Setting: Department of Dermatology, Burn and Accident Hospital, Yazd, Iran
Subjects: A total of 110 patients with psoriasis and 110 nonpsoriasis patients were enrolled in this study
Intervention: Data on age, sex, weight, height, waist circumference and blood pressure of all participants were obtained. Severity of psoriasis was assessed using Body Surface Area [BSA] as mild [< 2% BSA], moderate [3-10% BSA] and severe [>10% BSA]. Fasting venous blood samples were collected and the fasting glucose and lipid levels were measured
Main Outcome Measure: We assessed fasting glucose, lipid profile, blood pressure and metabolic syndrome
Results: The mean ages of the cases and controls were 14.80 +/- 39 years and 14.25 +/- 39 years, respectively. The results showed that hypertension is significantly more common in psoriatic patients compared with controls. There was no significant difference in BMI, diabetes mellitus and hyperlipidemia between two groups. Metabolic syndrome was detected in 27.3% of patients with psoriasis and 20.9% of the patients in control group but this difference was not statistically significant [P value = 0.270]
Conclusion: The results of our study revealed that there is no close association between psoriasis and metabolic syndrome in Yazd