RESUMO
Potassium is the major intracellular cation with concentrations reaching 120-150 mEq/L. On the contrary, the extracellular fluid potassium concentration is much lower and kept within very narrow levels between 3.5- 5.0mEq/L [1]
Aim of the work: this work aimed to assess serum potassium level in patients on regular hemodialysis and to determine its clinical impact on hemodynamic stability during the hemodialysis session
Patient and method: serum [K] level of 30 patients on regular hemodialysis was measured before and after dialysis and the results were correlated with electrocardiographic [ECG] changes
Results: there was no change in P wave, PR interval or QT interval in all the patients, while QRS was found to be shortened in 3 patients [10%] in the post-dialysis ECG and elongated in one patient [3.3%] in the post dialysis ECG, T wave showed dynamic changes in the form of reduction in the amplitude of T wave in 11 patients [36.7%]
Conclusion: the absence of electrocardiographic changes in hyperkalaemic haemodialysis patients should be interpreted with caution
RESUMO
OSA is associated with an increased prevalence of coronary artery disease heart failure and rhythm disturbance. Also, P-wave dispersion [Pd] reflects inhomogeneous atrial depolarization secondary to insults such as chronically elevated atrial pressure, ischemia, or metabolic stress that promote atrial structure remodeling and provide a substrate for atrial fibrillation. We aimed to investigate Pd in patients with OSA and to determine if there is any relationship with severity of the disease. This study was conducted in Chest and Cardiology Departments, Assuit University Hospital, Egypt on 40 OSA patients [29 males and 11 females], and 20 healthy controls. We excluded patients with COPD and any diagnosed cardiac disease. For every patient, we did a polysomnography and ECG. Pd was significantly more in OSA [98.50 +/- 4.77 m/s] than controls [72.00 +/- 3.37 m/s] Rvalue <0.05]. Pd in severe, moderate and mild OSA were 111.43 +/- 5.62 m/s, 95.00 +/- 7.83 m/s ando5.71 +/- 8.41 m/s, respectively with a significant positive correlation with severity of OSA. Multiple linear regression shows that systolic blood pressure and BMI are independently associated with Pd [beta = 0.56, p = 0.00] [beta = 0.27, p = 0.05]. Pd is increased and correlated with severity of OSA. Systolic blood pressure and BMI are independent risk factors for Pd. Follow up of patients to detect clinical implications is recommended