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Background:Diabetic foot ulcer is a serious complication of diabetes which results lower extremity amputation. Proper preventative measures, appropriate foot self-care and management of foot ulcer will reduce, delay or prevent the incidence of infection, gangrene, and amputation. This study was intended to assess diabetes patients‘ awareness and extent of foot care practice at University of Gondar referral Hospital. Methods:An institutional based cross-sectional study was conducted from Marchto June 2018. A total of 372 diabetes patients were included in this study. Data were collected through face to face interview using structured questionnaires. The datawere analyzed using SPSS version 20. Binary logistic regression analysis was conducted. A pvalue <0.05 was consisdered statitisticaly significant.Results:Of all participants more than half 197 (53%) were male. The age range of participants was 18-90 years. Majority, 65.6 % (with 95% CI 60.8-70.2) of diabetes patients had good foot self-care practice. Poor foot self-care practice was significantly associated with having poor level of awareness about foot care (AOR 12.55, 95% CI, 6.49-24.28) and having no previous information about foot ulcer (AOR 7.03, 95% CI, 2.11-23.46).Conclusions:Generally, in this hospital most of the study participants had good awareness and practices towards foot self-care. However,selectively majority of patients had poor foot self-care practice regarding; drying of their feet after every wash, change the socks/stockings/ used regularly, and avoid wearing of slippers with no fastening. Foot self-care practices were positively associated with having good awareness about foot care and having previous information about foot ulcer.
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Objective: To determine the prevalence, level of severity of potential drug-drug interactions (PDDIs) and the associated factors for PDDIs in hospitalized pediatric patients of Gondar University Hospital. Methods: A retrospective cross-sectional study was conducted for a period of 3 months from March to May 2014 in pediatric wards of Gondar University Hospital. Systematic random sampling technique was used to select charts from all pediatric patients' charts with every 7th interval to get sample size of 384. Univariate and multivariate analysis were performed to compute crude odds ratio and adjusted odds ratio respectively. Statistical significance was set at P value < 0.05. Results: A total of 176 (45.8%) patients had at least one PDDI. A total of 393 PDDIs, which were comprised of 283 types of interacting combinations, were identified. Of the total of 393 PDDIs, most were of moderate severity [201 (51%)] followed by minor [152 (39%)] and major severity [40 (10%)]. The most common interacting pairs of major severity were gentamicin + furosemide (6), cotrimoxazole + methotrexate (4) and phenytoin + artemether (4). The occurrence of PDDIs was significantly associated with age and polypharmacy. Conclusions: The study showed that most of the interactions had moderate severity followed by minor severity. Age and polypharmacy were found to show statistically significant association with the occurrence of PDDIs. Due to sensitive nature of pediatrics population, close monitoring is recommended for the detection and management of PDDIs to prevent its negative consequences.