RESUMO
In recent years, there has been an exponential interest in the development of novel drug delivery systems using nanoparticles. Nanoparticles can offer significant advantages over the conventional drug delivery in terms of high stability, high specificity, high drug carrying capacity, ability for controlled release, possibility to use in different route of administration and the capability to deliver both hydrophilic and hydrophobic drug molecules. This review focuses on classification, methods of preparation, characterisation, application, advantages of nanoparticles and health perspectives.
RESUMO
The use of extended-release products offers some potential advantages in patient convenience, compliance and therapeutic outcomes. However, the range of drugs for which clinically significant advantages have been shown is limited. Prescribers and pharmacists should be aware of these products and have knowledge of their clinical use in selected patient groups. In some instances, the formulation is probably serving a marketing objective rather than a clinical objective.