Necrotic erythema nodosum reaction associated with histological alterations of Lucio's phenomenon

Abstract Patients with lepromatous or borderline leprosy may present two types of vasculonecrotic reactions: Lucio's phenomenon (LP) and necrotic erythema nodosum leprosum (nENL). These are serious conditions, which mostly lead to life-threatening infectious and thrombotic complications. The authors report the case of a patient with leprosy recurrence associated with an atypical type II reaction with LP characteristics on histopathology.

Effect of Organic Residues as Fertilizer on Postharvest Quality of Cherry Tomatoes

Abstract Composting of domestic residues to replace cattle manure was evaluated as a fertilization option for the cherry tomato crop. Two sources of organic compounds (CO) were used to prepare compost piles: Domestic residues (DR) and bovine manure (BM), used in 5 proportions (CO1 = 15% DR + 15% BM, CO2 = 10% DR + 20% BM, CO3 = 20% DR + 10% BM, CO4 = 30% BM (control) and CO5 = 30% DR). To compost the compost piles, the organic waste (carbon source) was mixed with remnants of tree pruning (filler) from the urban cleaning service in a ratio of 1: 3. After 90 days, the compost from each matured pile was mixed with 1: 1 coconut fiber substrate and filled into 15 L plastic bags where the cherry tomato plants were grown. The experiment was conducted in a greenhouse using the experimental design of randomized blocks with 5 treatments and 5 replicates (6 fruits per sample). The organic fertilization in the proportions of manure and food residue did not provide statistically significant differences in soluble solids, total sugars, lycopene, β-carotene and micronutrients Zn, Fe, N and P in cherry tomato fruits. Fertilization with CO1 and CO2 increased AT, Mn and decreased the SS / AT, K and Ca ratio. There was no nutritional deficiency of tomatoes in any of the proportions of the organic residues studied.

Case for diagnosis. Infiltrated areas on the trunk

Abstract Leprosy is an infectious disease with chronic evolution, caused by Mycobacterium leprae, an acid-fast bacillus that mainly affects the skin and peripheral nervous tissue. Many of the clinical manifestations of leprosy can mimic connective tissue diseases. The authors present the case of a 49-year-old woman who had been treated for four years for systemic lupus erythematosus in a rheumatological service. Skin biopsy of a plaque on the inguinal region was compatible with borderline lepromatous leprosy associated with a type 1 lepra reaction. The patient is undergoing treatment with multibacillary multidrug therapy, showing clinical improvement.

Case for diagnosis. Pruritic erythematosquamous lesion in the auricle

Abstract Chromoblastomycosis is a subcutaneous mycosis with chronic evolution that mainly affects the lower limbs and, less frequently, the auricles. Clinically, it presents with papillary verrucous, nodular, and/or tumoral lesions, whether isolated or infiltrated, forming plaques and, sometimes, atrophic in some areas. Histopathologically, it is characterized by a dermal granulomatous inflammatory infiltrate, and the diagnosis can be confirmed by the presence of fumagoid bodies in anatomopathological or direct mycological exams. The treatment to be indicated will depend on the extent and location of the lesions, using systemic antifungals, surgical removal, cryotherapy, thermotherapy, and immunoadjuvants. The present study reports an atypical presentation of chromoblastomycosis on the auricle.

Yield and quality of cherry tomato fruits in hydroponic cultivation / Produção e qualidade de frutos de tomate cereja em cultivo hidroponia

Because of the food and industrial importance of tomato, it holds great significance, and is one of the most produced species using the hydroponic cultivation systems. The objective of this study was to evaluate the effects of different concentrations of nutrient solution on the production and quality of cherry tomatoes (Lycopersicon esculentum 'Samambaia') grown in a hydroponic system in protected conditions. The experiment was conducted in pots filled with coconut fiber substrate using a randomized complete block design with four replications and six plants per plot. Five concentrations of nutrients were evaluated (50, 75, 100, 125, and 150% of the standard nutrient solution); the solutions produced the following electrical conductivities: 1.8, 2.0, 2.6, 3.4, and 3.9 dS m-1, respectively. At 90 days after transplanting, the tomato fruits were harvested, at which time the production variables and post-harvest quality of mature fruits were determined. The best production and post-harvest quality indexes of cherry tomatoes ('Samambaia') were found when using 111% of the standard nutrient solution, corresponding to the concentrations of 9.44, 2.44, 2.22, 6.44, 4.11, 2.44, and 2.78 mmolc L-1, of NO3 - , NH4 + , P, K, Ca, Mg, and S, respectively; and 66.6, 55.5, 14.4, 1.89, 0.56, and 0.44 mmolc L -1, of Fe, B, Mn, Zn, Cu, and Mo, respectively. Nutrient solutions with electrical conductivity above 2.89 dS m-1 severely reduced the fruit yield of cherry tomatoes.

Devido à importância alimentar e industrial do tomateiro, a cultura destaca-se entre as hortaliças, sendo uma das espécies mais produzidas em sistema hidropônico de cultivo. Nosso objetivo foi avaliar os efeitos da aplicação de diferentes concentrações de solução nutritiva na produção e na qualidade dos frutos de tomate cereja (Licopersicon esculentum, cv. Samambaia) em sistema hidropônico sobre condição de ambiente protegido. O experimento foi conduzido em vasos preenchidos com substrato de fibra de coco utilizando o delineamento de blocos casualizados, com quatro repetições e seis plantas por parcela. Foram avaliadas cinco concentrações de nutrientes na solução nutritiva hidropônica (50, 75, 100, 125 e 150% da solução nutritiva padrão) que, após a diluição dos nutrientes em água de torneira, estas produziram as seguintes condutividades elétricas: 1.8, 2.0, 2.6, 3.4 e 3.9 dS m-1, respectivamente. Aos 90 dias após o transplantio, os frutos de tomate foram colhidos, ocasião em que se determinaram as variáveis de produção e qualidade póscolheita de frutos maduros. A análise dos resultados indicou que os melhores índices de produção e qualidade dos frutos de tomate cereja cultivado em sistema hidropônico foram encontrados nas concentrações de macronutrientes da solução nutritiva correspondente a 9,44; 2,44; 2,22; 6,44; 4,11; 2,44 e 2,78 mmolc L-1 de NO3 - , NH4 + , P, K, Ca, Mg e S, respectivamente, e 66,6; 55,5; 14,4; 1,89; 0,56 e 0,44 mmolc L-1, de Fe, B, Mn, Zn, Cu e Mo, respectivamente. As soluções nutritivas com condutividade elétricas acima de 2,89 dS m-1 reduziram severamente o rendimento de frutos de tomate cereja

Subcutaneous phaeohyphomycosis due to cladophialophora bantiana: a first case report in an immunocompetent patient in Latin America and a brief literature review

Abstract We report a rare case of subcutaneous phaeohyphomycosis caused by Cladophialophora bantiana in an immunocompetent patient in Amazonas, Brazil. This dematiaceous fungus has been mainly associated with life-threatening infections affecting the central nervous systems of immunosuppressed patients. We present the clinical, laboratory, and therapeutic aspects, and in vitro susceptibility test results for different antifungal drugs. A brief review of the cases reported in the literature over the past 20 years has also been discussed. According to the literature review, the present case is the first report of subcutaneous phaeohyphomycosis due to C. bantiana in an immunocompetent patient in Latin America.

Pigmented squamous cell carcinoma: case report and importance of differential diagnosis

Abstract: A few cases of pigmented squamous cell carcinoma affecting the skin and the ocular and oral mucosa of the elderly have been described in the literature. The disease manifests itself as papular and nodular erythematous or pigmented lesions. The main clinical differential diagnoses are pigmented basal cell carcinoma and melanoma. Histopathological examination is characterized by proliferation of atypical squamous cells with formation of horn pearls permeated by dendritic melanocytes. For this reason, a careful diagnosis is necessary to rule out other tumors that show melanin pigment. Surgical removal is the indicated treatment and the prognosis is similar to the classical squamous cell carcinoma. We report a case of pigmented squamous cell carcinoma with diagnosis confirmed by histological and immunohistochemical examinations.

Bioactive compounds and antioxidant activity of Ximenia americana coming from different collection sites

The study aimed to evaluate the bioactive compounds and antioxidant activity of edible fraction (pulp and peel) in green and ripe ripening stages of the fruit and the seed of wild plum (Ximenia americana L.) from different production sites of occurrence in the semiarid region of Brazil. To characterize the edible fraction, the experiment was conducted in a completely randomized design in a factorial 3 x 2, where the first factor was the collection sites and the second factor the maturation stages, with 4 repetitions with 25 fruits each. As for seeds the experiment was conducted in a completely randomized design with 4 repetitions, totaling 25 seeds per experimental plot. The fruits were collected in the communities of Mulunguzinho, Pau Branco and Mata do Meio in the county of Mossoró, RN, Brazil. The edible fraction of the fruit Ximenia americana contains high levels of vitamin C (160,26 mg/100 g), yellow flavonoids (43,12 mg/100 g), total extractable polyphenols (3066,48 mg/100 g) and antioxidant activity (365,55 g fruit/g DPPH e 251,70 μmol Trolox/g) and the seeds contain content of polyphenols (2067,56 mg/100 g) and antioxidant (373,80 g fruit/g DPPH e 279,96 251,70 μmol Trolox/g). The edible part of the green fruit contains higher content of total extractable polyphenols, total carotenoids, yellow flavonoids and total anthocyanins. The edible portion of the fruits and the seeds from the community of Pau Branco contains the lowest content of total extractable polyphenols and antioxidant activity(AU)

Compostos bioativos e atividade antioxidante de Ximenia americana oriunda de diferentes locais de coleta. O trabalho teve como objetivo avaliar os compostos bioativos e a atividade antioxidante da fração comestível (polpa e casca) nos estádios de maturação verde e maduro do fruto e da semente da ameixa silvestre (Ximenia americana L.) proveniente de diferentes locais de ocorrência de produção na região semiárida do Brasil. Para caracterização da fração comestível o experimento foi conduzido em delineamento inteiramente casualizado em esquema fatorial 3 x 2, sendo o primeiro fator os locais de coleta e o segundo fator os estádios de maturação, com 4 repetições com 25 frutos cada. Já para as sementes o experimento foi conduzido em delineamento inteiramente casualizado, com 4 repetições, totalizando 25 sementes por parcela experimental. Os frutos foram coletados nas comunidades de Mulunguzinho, Pau Branco e Mata do Meio, no município de Mossoró, RN, Brasil. A fração comestível do fruto da Ximenia americana contém elevados teores de vitamina C (160,26 mg/100 g), flavonoides amarelos (43,12 mg/100 g), polifenóis extraíveis totais (3066,48 mg/100 g) e atividade antioxidante (365,55 g fruit/g DPPH e 251,70 μmol Trolox/g) e as sementes elevados teores de polifenóis (2067,56 mg/100 g) e atividade antioxidante (373,80 g fruit/g DPPH e 279,96 251,70 μmol Trolox/g). A fração comestível do fruto verde contém maior conteúdo de polifenóis extraíveis totais, carotenoides totais, flavonoides amarelos e antocianina totais. A fração comestível e as sementes dos frutos provenientes da comunidade de Pau Branco contém menor conteúdo de polifenóis extraíveis totais e atividade antioxidante(AU)

Qualidade pós-colheita da banana 'Prata Catarina' submetida a diferentes danos mecânicos e armazenamento refrigerado / Postharvest quality of 'Prata Catarina' banana submitted to different mechanical damages and refrigerated storage

Objetivou-se avaliar o efeito dos danos mecânicos provocados por impacto, corte e abrasão sobre a qualidade de banana 'Prata Catarina', submetida ao armazenamento refrigerado (14°C ±1ºC e 84% ±5% de UR durante 21 dias). Os frutos foram provenientes de um pomar comercial, localizado no município de Limoeiro do Norte-CE. O experimento foi instalado em delineamento inteiramente ao acaso, no esquema de parcelas subdivididas no tempo, tendo-se, nas parcelas, as amostragens ao longo do tempo e, nas subparcelas, os quatro tratamentos: testemunha ou ausência de dano mecânico (T1), impacto (T2), abrasão (T3) e corte (T4), com quatro repetições de dois frutos cada. Os danos por impacto e abrasão foram os que proporcionaram maior velocidade de amadurecimento, sendo que o dano por impacto proporcionou maior atividade da enzima polifenoloxidase. As bananas 'Prata Catarina' que não sofreram danos podem ser comercializadas por até 21 dias de armazenamento (14°C ± 1ºC e 84% ±5% UR), sem perda da qualidade.

The aim of this study was to evaluate the effect of mechanical damages caused by impact, cut and abrasion on the quality of 'Prata Catarina' banana subjected to cold storage (14°C±1°C and 84%±5% RH for 21 days). The fruits were from a commercial orchard in the city of Limoeiro do Norte-CE. The experiment was conducted in a completely randomized design in split plot in time, taking up the samples in portions over time and in the subplots the four treatments: control or absence of mechanical damage (T1), impact (T2), abrasion (T3) and cut (T4), with 4 replicates of 2 fruits. Damages by impact and abrasion were the ones which provided the highest speed of ripening, and the damage caused by impact provided greater polyphenoloxidase enzyme activity. 'Prata Catarina' bananas that suffered no damage can be marketed until 21 days of storage (14°C±1°C and RH 84%±5%), without loss of quality.

Case for diagnosis

We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present with tumoral lesions on one or both legs (worst prognosis). Diagnosis is based on clinical, histopathological and immunohistochemical findings. The strong expression of BCL2, BCL6, MUM-1 and CD20, and the positivity for Ki67 antigen confirm the diagnosis. R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) is the most widely accepted treatment.

Prototipagem rápida aplicada a implantodontia: obtenção e uso

A prototipagem, representada em forma de dados em um computador, é capz de reproduzir fisicamente, em vários tipos de materiais, um modelo virtual. As técnicas de prototipagem mais utilizadas são: estereolitografia, sinterização seletiva a laser, impressão tridimensional, modelagem por deposição fundida...

Aspectos clínicos de pacientes com pitiríase versicolor atendidos em um centro de referência em dermatologia tropical na cidade de Manaus (AM), Brasil / Clinical aspects of patients with pityriasis versicolor seen at a referral center for tropical dermatology in Manaus, Amazonas, Brazil

FUNDAMENTOS: A pitiríase versicolor (tinha versicolor) é uma micose superficial crônica, causada por leveduras do gênero Malassezia spp. comensais das camadas queratinizadas da pele e que, sob determinadas condições ainda não esclarecidas, se torna patogênica, determinando as manifestações clínicas da doença. É uma dermatose recidivante e, mesmo após tratamento, pode deixar hipopigmentação persistente, causando problemas sociais aos indivíduos acometidos. OBJETIVO: Descrever as características clínicas e epidemiológicas de pacientes com diagnóstico de tinha versicolor atendidos em uma unidade de referência em Dermatologia (Fundação Alfredo da Matta). MÉTODOS: Estudo de série de casos em que foram detalhadas as manifestações cutâneas e as características epidemiológicas de pacientes atendidos na Fundação Alfredo da Matta com diagnóstico de tinha versicolor. RESULTADOS: Cento e dezesseis pacientes foram incluídos no estudo no período de janeiro a agosto de 2008. A maioria dos indivíduos é do sexo masculino, de cor parda, da faixa etária jovem e formada por estudantes, que apresentavam fatores predisponentes ao surgimento das manchas. Também a maioria apresentava lesões extensas e história passada da doença. CONCLUSÃO: O estudo mostrou alta proporção de indivíduos com quadros extensos e de longa duração da doença.

BACKGROUND: Pityriasis versicolor (tinea versicolor) is a chronic superficial mycosis caused by yeasts of the Malassezia spp. genus commensal of the keratinized layers of the skin. Under conditions not yet understood, it becomes pathogenic determining the clinical manifestations of the disease. It is a recurrent skin condition and persistent hypopigmentation may remain after treatment, causing social problems to those affected. OBJECTIVE: To describe the clinical and epidemiological features of patients diagnosed with tinea versicolor treated at a referral center for dermatology (Alfredo da Matta Foundation). METHODS: Case-studies in which cutaneous manifestations and epidemiological characteristics of patients diagnosed with tinea versicolor treated at Alfredo da Matta Foundation were detailed. RESULTS: One hundred and sixteen patients were included in the study from January to August 2008. Most subjects were male, of mixed ethnicity and young age. Most were students who were predisposed to the development of macules. The majority had extensive injuries and past history of the disease. CONCLUSION: The results revealed a high proportion of individuals with extensive clinical manifestations and duration of the disease.

Índice de necessidade de tratamento odontológico: o caso dos índios Xakriabá / Rate of dental treatment needs: the case of the Xakriaba Indians

O presente trabalho, desenvolvido com os índios Xakriabá, em Minas Gerais, teve como objetivo conhecer as necessidades de tratamento odontológico buscando organizar o agendamento dos pacientes para tratamento. Os Agentes Indígenas de Saúde foram treinados por cirurgiões-dentistas para realizarem o levantamento nos domicílios. A população indígena total é de 6.498 habitantes, sendo que 3.686 estão na área de abrangência do Pólo Base Brejo Mata Fome, local onde 61 por cento das pessoas foram examinadas. Os resultados mostraram haver uma população predominantemente jovem, um grande número de pessoas sem necessidade de tratamento e a cárie dentária foi o problema mais prevalente. Espera-se que o levantamento de necessidades venha contribuir para um agendamento no qual as pessoas que apresentam situações mais graves sejam priorizadas, buscando com isso promover a eqüidade.

The present study was developed among Xakriabas Indians in Minas Gerais and aimed at identifying their needs for dental treatment so that patients could be scheduled for treatment. Native health agents were trained by dental-surgeons for conducting the survey in household visits. The total Indian population is of 6.498 inhabitants, 3.686 of these living within the territory of the "Base Mata Fome", where 61 percent of the population was examined. Results showed that the population is mainly young, a great number of individuals presented no need for treatment and dental caries was the most frequent problem. The survey is expected to help in the organization of a schedule that allows giving priority to the more serious cases and promoting equity.

Tumor de Bednar (dermatofibrossarcoma protuberante pigmentado): relato de um caso / Bednar tumor ( pigmented dermatofibrosarcoma protuberans): a case report

O tumor de Bednar é uma rara neoplasia da pele, considerada variante pigmentada do dermatofibrossarcoma protuberans. O diagnóstico é confirmado pelo exame histopatológico e estudo imuno-histoquímico. O tumor de Bednar é agressivo localmente, recidivando com freqüência, mas raramente ocorrem metástases. O procedimento terapêutico mais adequado é a cirurgia micrográfica de Mohs. Relata-se o caso de uma paciente de 35 anos, portadora dessa rara neoplasia, cujo diagnóstico foi estabelecido por exame histopatológico e estudo imuno-histoquímico. Ressalta-se a importância de o dermatologista estar atento para suspeitar do diagnóstico e dispor dos meios necessários para confirmá-lo, adotando a melhor conduta