Can a dentin bonding agent prevent color change in regenerative endodontic procedures? An in vitro evaluation

Abstract This in vitro study aimed to determine the efficacy of dentin bonding agents in preventing color changes following Regenerative Endodontic Procedures. One hundred twenty bovine incisors were endodontically prepared and randomly assigned to a two main factors design: application of a dentin bonding agent (Scotchbond Adper, 3M ESPE, St Paul, MN, USA) in the pulp chamber (Group 1, n=60) versus no bonding intervention (Group 2, n=60), and five levels of intracanal medication (n=12/subgroup): Triple antibiotic paste (TAP), double antibiotic paste (DAB), calcium hydroxide (CH), modified triple antibiotic paste (TAPM), and Control (CTL). Color changes were measured over 28 days at multiple time points (1, 3, 7, 14, 21, and 28 days) using the CIEDE2000 formula to calculate the color difference (ΔE00) from baseline (T0). The ΔE00 quantifies the perceptible color difference between the initial and final tooth color, with lower values indicating less discoloration. The results were analyzed using repeated measures ANOVA-2 and post-hoc Holm-Sidak tests. The TAP subgroups, both with and without the bonding agent, exhibited the highest color variation. However, a pulp chamber seal with a bonding agent showed a protective effect against discoloration compared to no seal, even though complete prevention was not achieved. All groups demonstrated ΔE00 values beyond acceptable interpretation thresholds for clinical application, primarily driven by a reduction in lightness (L*) and a decrease in redness (a* value, shifting towards green). In conclusion, while the pulp chamber seal with a bonding agent mitigated TAP-induced discoloration, it did not eliminate it.

Resumo Este estudo in vitro avaliou adesivos dentinários na prevenção de alterações de cor após procedimentos endodônticos regenerativos. Cento e vinte incisivos bovinos foram preparados endodonticamente e aleatoriamente designados para um desenho com dois fatores principais: aplicação de agente adesivo (Scotchbond Adper, 3M ESPE, St Paul, MN, EUA) na câmara pulpar (Grupo 1, n=60) versus não intervenção adesiva (Grupo 2, n=60), e cinco níveis de medicação intracanal (n=12/subgrupo): pasta de triantibiótica (TAP), pasta diantibiótica (DAB), hidróxido de cálcio (CH), pasta triantibiótica modificada (TAPM) e Controle (CTL). Alterações cromáticas foram monitoradas por 28 dias em intervalos (1, 3, 7, 14, 21, e 28 dias), usando CIEDE2000 para calcular a diferença de cor (ΔE00) em relação a cor inicial. O ΔE00 quantifica a diferença entre a cor inicial e final do dente, com valores menores indicando menos descoloração. Os resultados foram analisados usando ANOVA-2 de medidas repetidas e teste posthoc de Holm-Sidak. Os grupos utilizando medicação TAP, com ou sem adesivo, possuíram as maiores variações cromática. Contudo, o uso do adesivo na câmara pulpar mostrou um efeito protetor contra descoloração, em comparação com a ausência do selamento adesivo, embora a prevenção completa não tenha sido alcançada. Todos os grupos demonstraram valores de ΔE00 além dos limiares aceitáveis para aplicação clínica, principalmente devido à redução na luminosidade (L*) e redução no vermelho (a*, deslocando-se em direção ao verde). Em conclusão, enquanto o selamento da câmara pulpar com um agente adesivo mitigou a descoloração induzida pelo TAP, mas não a eliminou completamente.

A Bibliometric analysis of articles published in Brazilian Dental Journal over 30 years

Abstract This study assessed bibliometric characteristics of all articles published in Brazilian Dental Journal (BDJ) in its 30 years of existence (1990-2019) and factors associated with citation rates. A document search was carried out in Scopus in December, 2019 and information about the articles were exported, including citations. Type of study and main subject in each article were categorized. Number of citations was categorized in tertiles. Logistic regression models were used to assess the association between variables related to articles' characteristics and number of citations. In 30 years, 1705 articles were published and 18507 citations received, with average 57 articles and 334 pages published yearly and 10.9 cites/doc. The most frequent types of study were laboratorial (63%), clinical (18.5%), and case reports (11%); the main subjects were dental materials (21.6%), endodontics (19.3%), and oral pathology/stomatology (13.1%). Most articles had origin in Brazil (90%), followed by USA (4.6%) and UK (1.5%). Aside from BDJ, Journal of Endodontics (3.5%) and International Endodontic Journal (2.2%) were journals that most often cited BDJ. Main origins of citations were Brazil (36.7%), USA (10.6%), and India (9%). Older articles had higher odds to be highly cited (12% increase/year), longer articles had lower odds (9% decrease/page). Narrative reviews and epidemiological studies were associated with more citations and systematic reviews with less citations. In conclusion, BDJ covered many subjects and study types in 30 years, showing increased growth in international audience. The journal may be regarded as one of the leading Brazilian journals in dentistry published in English.

Resumo Este estudo avaliou as características bibliométricas de todos os artigos publicados no Brazilian Dental Journal (BDJ) em seus 30 anos de existência (1990-2019) e fatores associados com taxas de citação. Uma busca pelos documentos foi realizada no Scopus em Dezembro de 2019 e informações acerca dos artigos foram exportadas, incluindo citações. Tipo de estudo e principal assunto em cada artigo foram categorizados. Número de citações foi categorizado em tercis. Modelos de regressão logística foram usados para avaliar a associação entre as variáveis relacionadas às características dos artigos e o número de citações. Em 30 anos, 1705 artigos foram publicados e 18507 citações recebidas, com média de 57 artigos e 334 páginas publicadas ao ano e 10,9 citações/documento. Os tipos de estudo mais frequentes foram laboratorial (63%), clínico (18,5%) e relato de caso (11%); os principais assuntos foram materiais dentários (21,6%), endodontia (19,3%) e patologia oral/estomatologia (13,1%). A maioria doas artigos teve origem do Brasil (90%), seguido dos EUA (4,6%) e Reino Unido (1,5%). Além do BDJ, Journal of Endodontics (3,5%) e International Endodontic Journal (2,2%) foram os periódicos que mais citaram o BDJ. As principais origem das citações foram Brasil (36,7%), EUA (10,6%) e Índia (9%). Artigos mais antigos tiveram maiores chances de serem altamente citados (aumento de 12% ao ano), artigos mais longos tiveram menores chances (redução de 9% por página). Revisões narrativas e estudos epidemiológicos foram associados com mais citações e revisões sistemáticas com menos citações. Em conclusão, o BDJ cobriu diversos assuntos e tipos de estudo em 30 anos, mostrando contínuo crescimento na audiência internacional. O periódico pode ser considerado um dos líderes entre as revistas brasileiras de odontologia publicadas em inglês.

Prevalence of risk factors for denture stomatitis in complete denture wearers

Aim: The prevalence of denture stomatitis and the relationship with its risk factors was evaluated via secondary data from 62 complete denture (CD) wearers, between 2015 and 2017. Methods: The data was stored in an Excel database and was analyzed using the statistics software STATA/SE 12.0. A descriptive analysis was performed taking into account a categorization of the clinical variables according to risk factor in 4 domains: CD usage, systemic health, hygiene habits, and usage habits. The association amongst the denture stomatitis and risk factors variables was tested by the Chi-square test and the results were statistically significant at p-values <0.05. Results: The CD wearers participants were composed by a majority of elderly (80.64%) and women (72.78%); with 45.16% having been using the current denture for more than 10 years and another 74.19% related a continuous usage. Diabetes and hypertension were related by 83.87% and 67.74%, respectively, with 87.10% using medication. Although 75.80% reported cleaning their dentures 3 times per day or more, and 59.68% considered their oral hygiene very good, 50% of the complete dentures showed dirtiness and clinical signs of Denture Stomatitis were present in 30.64% of the patients. Despite of the evaluated sample shows many risk factors for the development of the disease, an association between the variables was not observed. Conclusion: Considering the high prevalence of the disease in the studied sample, preventive and educational measures on denture usage and hygiene must be reinforced in order to maintain the oral health of the edentulous patients

Caracterización general de Lactarios de Hospitales de Referencia de Asunción y Departamento Central

Introducción: Los lactarios iniciaron sus actividades en los hospitales de nuestro medio, con el objetivo de contribuir al mantenimiento del estado nutricional y a la recuperación de la salud de los pacientes hospitalizados, a través de una intervención nutricional de excelencia técnica. Objetivo: Caracterizar los Lactarios de Hospitales de Referencia de Asunción y Central, durante el periodo 2014, para establecer un diagnóstico de la situación de adecuación de los mismos a las normas internacionales. Materiales y Métodos: Diseño descriptivo, observacional. Se utilizó una encuesta a partir del documento "Orientaciones técnicas para Servicios Dietéticos de Leche (SEDILE) y Central de Fórmula Enteral (CEFE) del Ministerio de Salud de Chile. Se realizó observación directa de los lactarios y encuesta a los profesionales encargados. Estadística: A cada variable de las dimensiones evaluadas en los lactarios se le asignó una puntuación de acuerdo a la presencia (1) o ausencia (0) de la característica estudiada y estos resultados se compararon al 100% de los datos del instrumento de recolección. Las variables obtenidas fueron cualitativas, dicotómicas (presencia o ausencia) y para su descripción se utilizó la distribución de frecuencia en porcentajes. Para las variables cuantitativas se utilizaron las medidas de tendencia central y dispersión. Resultados: Ingresaron al estudio siete lactarios de hospitales públicos, dos de los cuales fueron para extracción de leche materna. En relación a la disponibilidad de: 1) Recursos físicos: el porcentaje (%) global fue del 55% (rango 38-80%). 2) Equipamiento: el % global fue del 42% (rango 27-62%). 3) Manual de funciones y organigrama: el % global fue del 55% (rango 25-75%). 4) Normas y procedimientos: el % global fue del 59% (rango 27-80%). Conclusiones: La dimensión más afectada en los lactarios evaluados fue el equipamiento, seguida de recursos físicos y la disponibilidad de manual de funciones y organigrama.

Introduction: The lactary became active in Paraguayan hospitals to contribute to maintain or restore the nutritional health of hospitalized patients through nutritional intervention. Objetive: To characterize the lactary operating at reference hospitals in Asuncion and the Central Department, in 2014, to determine their adequacy to international standards. Materials and Methods: We conducted a descriptive and observational study by direct observation of the lactary and a survey, based on the guidelines of SEDILE (technical guidelines for dietary milk services) and CEFE (enteric formula center). Statistics: Each variable assessed by SEDILE criteria was assigned a point value according to the presence (1) or absence (0) of the particular criterion and compared to the total data collected in the survey. Variables determined were qualitative and binary (presence or absence), and described with percentage frequency distribution. Central tendency and dispersion measures were used for quantitative variables. Results: Seven lactary from public hospitals were included, of which two were dedicated to extraction of breast milk. Overall availability of physical resources was 55% (range 38-80%), of equipment, 42% (range, 27-62%), of organization charts and job description manuals, 55% (range, 25-75%), and standard and procedures manuals 59% (range, 27-80%). Conclusions: The greatest shortfall in the lactary studied was of equipment, followed by physical resources and organization and job function manuals.

Sistema de distribución de medicamentos mediante dosis unitaria / System of drugs distribution through unitary dosage

La Farmacia Asistencial del Hospital de Carabineros de la Sede Colón, tiene una experiencia de cinco años, aplicando el Sistema de Distribución de Medicamentos mediante Dosis Unitaria, cuyo principio fundamental, consiste en suministrar a cada paciente, el número de dosis necesarias de cada medicamento prescrito, para un período máximo de 24 horas. Este sistema se aplica a todos los Servicios Clínicos del Hospital, incluyendo las Unidades de Pacientes Críticos, la experiencia acumulada ha sido favorable y se concluye que es un seguro y eficiente sistema de dispensación de medicamentos