CT colonography - towards applications for colorectal cancer screening.

Three-dimensional (3D) imaging of the large intestine is globally called computed tomography colonography (CTC). CTC has been intensively investigated for application in colorectal cancer screening in Western countries and with the advent of multi-slice CT (MSCT), which provides effective high resolution in 3D CT images, the diagnostic use of CT for colorectal lesions has become a concept widely accepted throughout the world. Computer-aided detection (CAD) for colorectal polyps using digital CT image data and digital pre-processing are also advancing in the West. Compared with colonoscopy, which depends largely on the skill of the performer, CTC produces objective and reproducible diagnostic images and presents a high probability of standardizing examination protocols. Development of effective systems for screening colorectal lesions is expected, leveraging the excellent processing capability of MSCT to enhance 3D visualization and allow efficient detection.

The correlation study of radiological findings with pathological classification of superficial depressed (Ⅱc type)early gastric cancer / 中华放射学杂志

Objective To investigate the relations between radiological findings and pathological classification of superficial depressed(Ⅱc type)early gastric cancer.Methods Radiological features in subtonic double contrast barium examination and the endoscopic pictures of early gastric cancer compared with the global pathological specimens and micro-pathological features were prospectively studied.Combined with the gastric endoscopic pictures,the sharpness of margin of the lesions,the changes of converging mucosal folds and the changes of the depressed surface on the film of double contrast barium examination were analyzed.The correlation between the radiological features and histological classification of gastric cancer including well differentiated tubular adenocarcinoma(tub1),moderately differentiated tubular adenocarcinoma(tub2),poorly differentiated adenocarcinoma(por)and signet-ring cell carcinoma(sig) were studied.Results In 102 cases of Ⅱc type early gastric cancer,there were tubl 27 cases,tub2 11, por 26 and sig 38 cases histologically.The margin of the depressed lesions of tub1(24 cases)and tub2 (9 cases)cancers were mostly unsharply demarcated or with fine spicular border,while the margin of lesions of por(15 cases)and sig(31 cases)were mostly clearly and sharply demarcated,with statistical significance (P