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1.
IJPR-Iranian Journal of Pharmaceutical Research. 2014; 13 (3): 1097-1104
em Inglês | IMEMR | ID: emr-196727

RESUMO

The biological activity and composition of the essential oil of Sclerorhachis leptoclada Rech. an endemic species from northeast of Iran was studied. The essential oil was isolated from the aerial flowering parts of the plant and analyzed by GC and GC-MS. Fifty-four compounds accounting for 95.9% of the total oil were characterized. The main constituents were [E]-nerolidol [14.5%], terpinen-4-ol [13.3%], camphor [6.1%], 1,8-cineole [4.8%] and p-cymene [4.5%]. The antimicrobial activity of the essential oil of S. leptoclada was tested against eight microbial strains and a fungi. The results of the bioassays showed that the Gram-positive bacteria, Bacillus subtilis and Staphylococcus epidermidis, were the most sensitive to the oil than others with the MIC value of 1.8 mg/mL. The tested fungi, Saccharomyces cerevisiae was highly inhibited by the oil of S. leptoclada with MIC value of 10 mg/mL. In the case of cytotoxicity, IC50 values estimated to be 312, 1250, 625 and 1250 microg oil/ml respectively, for the Vero, SW480, MCF7, and JET 3 cancer cell lines

2.
Journal of Paramedical Sciences. 2012; 3 (2): 12-18
em Inglês | IMEMR | ID: emr-195729

RESUMO

Essential oils are volatile, natural, complex compounds formed by aromatic plants as secondary metabolites. In nature, essential oils play an important role in protecting plants in form of antibacterials, antivirals, antifungals, insecticides properties and also against herbivores. They also may attract some insects to use them in dispersion of pollens and seeds, or repel undesirable others. Present study describes the results of our study on the chemical composition, and antimicrobial activity of the essential oils from aerial parts of aromatic plants which collected from province of Tehran. The aerial parts of plants were collected at full flowering stage. The essential oils were isolated by hydrodistillation and analyzed by combination of capillary GC and GC-MS. Also their antimicrobial activities were considered according to the disc diffusion method and MIC values. Finally, five plant species [Salvia sclarea, salvia multicaulis, salvia verticillata, salvia limbata, Salvia choloroleuca] which showed good significant antibacterial were presented. These five plants belong to labiates' family. Among these proposed plants salvia multicaulis and Salvia sclarea showed good antibacterial activity

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