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1.
Braz. j. med. biol. res ; 24(7): 747-51, 1991. tab
Artigo em Inglês | LILACS | ID: lil-99514

RESUMO

In view of the correlation of the circadian system with the estrous cycle in the rat, some investigators have proposed the induction of polycystic ovaries by exposing rats to continuous light. However, there is divergence with respect to time of exposure and light intensity. in the present paper we propose a simple and efficient experimental model for the study of polycystic ovarian physiopathology in rats. Twenty female Wistar rats weighing 200-220 g were initially submitted to a 14-h light/10-h dark cycle. of the animals with regular estrous cycles, 9 were exposed to continuous light (600 lux) for 74 days (group 1) and 6 remained under the initial lighting conditions. A daily vaginal smear was used as indirect evidence for the changes in the estrous cycle. Plasma gonadotropin measurement and histological ovarian analysis showed that 90% of the animals in group 1 developed cystic follicles with the absence of the corpus luteum, despite the lack of reduction in ovarian weight commonly observed under 24-h lghting. This observation may be explained by the reduced time of stress to which the animals were submitted, since polycystic ovarian development occurred within less than 75 days of continuous exposure to 600-lux light, a time relatively shorter than commonly reported in the literature


Assuntos
Animais , Ratos , Feminino , Síndrome do Ovário Policístico/fisiopatologia , Ritmo Circadiano/fisiologia , Ritmo Circadiano/efeitos da radiação , Modelos Animais de Doenças , Estro/fisiologia , Estro/efeitos da radiação , Luz/efeitos adversos , Tamanho do Órgão , Ovário/anatomia & histologia , Síndrome do Ovário Policístico/patologia , Ratos Endogâmicos , Fatores de Tempo
2.
J. bras. ginecol ; 91(6): 485-7, 1981.
Artigo em Português | LILACS | ID: lil-5649

RESUMO

Os autores tecem comentarios sobre a sindrome da sela vazia, principalmente sobre o aspecto da secrecao endocrina nesses pacientes e apresentam dois casos de suas observacoes. Um dos casos nao apresentava alteracoes na secrecao endocrina, apesar da infertilidade secundaria de 12 anos e polimenorreia. O outro caso tinha prolactina basal alta e nao respondeu ao teste da L-Dopa


Assuntos
Síndrome da Sela Vazia
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