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Study of endometrial thickness is central to the monitoring of ovulation in in vitro fecondation [IVF]. Actually, failures of in vitro fecundation are mainly due to implantation failure of embryo. To assess whether the endometrial thickness the day of the induction of ovulation influences or not the result of the IVF attempt. To determine the endometrial thickness for which the chances of pregnancy are the highest. To determine if there is any effect of the stimulation protocol or the gonadotrophin on the endometrial thickness. A retrospective study at the Reproductive Medicine-Unit of Farhat Hached teaching hospital, Sousse -Tunisia, concerning all the cases of IVF conducted the year 2008. A total of 414 cycles of IVF were studied. The rate of pregnancies in our series was 23%. There was not statistically significant relation-ship between the women's-age and the endometrial thickness; nor between the rate of the ?stradiol before the IVF trial and the endometrial thickness. The endometrial thickness after ovarian stimulation was significantly linked to the rate of FSH before the IVF attempt [P = 0.01]. The total rate of pregnancies was significantly linked to the endometrial thickness before the ovulation induction [P = 0.02]. The best rate of pregnancy was reached with an endometrial thickness >12 mm [43%] and the chances of success in that case were roughly 3 times higher than if the endometrial thickness was
RESUMO
evaluation of our experience in assisted fertilization by ICSI with analysis of prognostic factors. retrospective study of 199 cycles of ICSI during a 2 years and half period between September 2001 and February 2004. The procedure of ICSI included several stages: collection and preparation of the semen, stake in culture of oocytes, removing of cumulus cells and microinjection of oocytes, control of the fertilization and embryo transfer respectively 18 to 22 hours and 48 hours after the microinjection. the mean age of the patients was 32,4 years and the mean duration of infertility was 7 years. The mean fertilization rate was 50%. The mean number of embryos transferred was 2.46. We got 41 pregnancies of which 36 were clinical pregnancies [87.8%]. The pregnancy rate was 26.1% by transfer and 21% by retrieval. The women age was the first prognostic factor of ICSI. The pregnancy rate was 27% before the age of 35 years, decreases with age and annul himself after 40 years [P=0.02]. The other prognostic factor was the number of 4 cells embryos transferred. The pregnancy rate increases with significant way with the number of 4 cells embryos transferred: 15% after transfer of only one embryo versus 43% after transfer of 3 embryos or more [P=0.04]. The ICSI prognostic has not been influenced with significant way by the origin or the sperm mobility, by the duration of infertility and by the total number of embryos transferred. the ICSI represents currently the treatment of choice of couple having extreme spermatic changes. The results of our study are comparable to those reported in the literature. The women age and the number of 4 cells embryos transferred are the main factors predicting of the ICSI prognostic