An observational study to determine the incidence and the clinico-epidemiologic profile of dengue fever in paediatric age group presenting to a tertiary care centre in Western Rajasthan, India

Background: Dengue remains major public health concern because of the expanding geographic distribution of both the virus and the mosquito vector. Aims and objectives was to determine the incidence of dengue fever in paediatric age group presenting to a tertiary care centre in Western Rajasthan and to evaluate the clinico-epidemiologic profile of these children.Methods: This is observational epidemiological study on patients of pediatric age group, over a period of one year.Results: A total of 210 ELISA positive cases, comprising of 55% males and 45% female (Male to female ratio of 1.2:1) were enrolled. In this study most (44.7%) were age group of 10-18 years, 80% patients from urban area, 93.8%. admitted between the months of September to December, 70.95% presented between 3rd to 5th days of their illness, 48 (22.86%) were tourniquet test positive at the time of admission with fever being most common (95.23%) presenting symptom, followed by headache (60%) and vomiting (55%). Almost all (99.52%) had thrombocytopenia (34.2% of them had severe thrombocytopenia), most (85%) had a hospital stay of less than a week, 98.10% patients required fluid therapy for less than 5 days. and a mean of 3.41'2.60 days were required by these patients to recover from significant thrombocytopenia. Here 22% (46) patient's required ICU care, with shock being main indication for ICU admission, followed by requirement of blood product transfusion (73%). Bleeding manifestations were seen in '73(34%) patients, commonest being the epistaxis in 40 patients (55%).Conclusions: Incidence of dengue was 0.42% with 32.38%patients were IgG ELISA positive also.

Fetal transverse cerebellar diameter measurement in intrauterine growth restriction: a more accurate parameter for gestational age assessment at term

Background: Assessment of fetal gestational age (GA) is an essential part of obstetric USG. Accurate knowledge of fetal GA is important to facilitate the best possible prenatal care and successful pregnancy outcome.  For the estimation of GA the commonly used parameters in third trimester are:- BPD, HC, AC and FL. As all these parameters are affected by fetal growth disorders and fetal position. TCD can be used as another parameter for the estimation of GA in growth restricted fetuses.Methods: This study was conducted at Mahila Chikitsalaya Sanganeri Gate; SMS Medical College Jaipur from July 2005 to September 2006. A total of 80 pregnant women in third trimester with singleton pregnancy including 40 pregnant women with known cases of IUGR and 40 AGA fetuses were studied for TCD measure.Results: Correlation coefficient between TCD and gestational age was highly significant and no significant difference was found in TCD of AGA and IUGR fetuses.Conclusions: TCD measurement can be used as more reliable parameter for accurate estimation of gestational age in IUGR fetuses in third trimester.