Drug-induced Capillary Leak Syndrome

Capillary leak syndrome is a disease with a high mortality rate. Its signs and symptoms are nonspecific. Generalized edema, hypotension, hypoproteinemia, and hemoconcentration are the characteristics of capillary leak syndrome. Here we report three cases of capillary leak syndrome developed after being treated with gemcitabine and paclitaxel. Immediate treatment with corticosteroids may be life-saving.