Diagnosis of pseudoxanthoma elasticum [PXE] from patients presenting with bleeding per rectum

To find out rare cause of bleeding per rectum in young patients in our study of 200 patients presenting with bleeding per rectum. Department of Medicine, Nishtar Hospital, Multan. Durations From July 1998 to July 2000. Two hundred patients presenting with bleeding per rectum were studied. History, general physical examination and systemic examination were done. Then provision clinical diagnosis was made and related investigations were done to confirm the diagnosis. Out of these 200 patients, 164 patients were diagnosed as having bleeding esophageal varices due to cirrhosis of liver. 22 patients were diagnosed as having gastritis [commonly drug induced] on endoscopy, 6 patients were having bleeding hemorrhoids, 3 patients were having bleeding gastric ulcer and 5 patients were diagnosed as having PXE. When young patients presented with bleeding per rectum and if diagnosis become difficult, then PXE must be considered in these patients and investigated properly

Study of 30 Cases of FUO [Fever of Unknown Origin]

To diagnose cause of Prolonged fever in patients suffering from FUO. Patients suffering from FUO were admitted in Medical Ward in Nishtar Hospital Multan and investigations were done to find out the cause of FUO. Medical Ward, Nishtar Hospital, Multan from 1.7.1998 to 30.6.2000. Patients presenting with FUO were admitted and investigated. Out of 30 patients of FUO, causes of FUO in 27 patients were diagnosed and in 3 patients, cause of FUO could not be established but these 3 patients responded to ATT [ANTI-Tuberculous Therapy]. It has been concluded that patients suffering from FUO becomes a challenge for treating. Physician and with Intensive investigations causes of FUO can be determined in most patients and in those patients in whom causes can not be identified these can be treated with ATT and most patients respond to ATT, confirming the diagnoses of hidden Tuberculosis

Association of dyslipidemia with acute and myocardial infarction

Ischaemic heart disease is a leading cause of death throughout the world. CAD has been recognized among all age groups especially above forty years of age more frequently in recent years. To determine the dyslipidaemia and waist hip ratio as a risk factor of Myocardial Infarction [MI]. This descriptive comparative type of study was conducted in the medical Ward, Nishtar Hospital, Multan during the period from January 2006 to January 2007. A total of 150 patients of first acute myocardial infarction age ranges from 35 years-70 years were included in the study. Among these patients 74% were males and 26% females. Two modifiable or controllable risk factors including dyslipidaemia. [Truncal obesity] were studied in this study. Patients were diagnosed on he bases of typical history of chest pain, ECG changes, raised cardiac enzymes or troponin T positive. Fasting lipid profile was done. Dyslipidaemia i.e. high total cholesterol, low density lipoproiein cholesterol and low HDL-cholesterol was statistically significant in all patients of ML 74% patients have dyslipidaemia including high total cholesterol, high LDL-C and low HDL-C. Triglyceride level was not found statistically significant. Incidence of IHD showed linear relation with age i.e. risk increased with the age only 14% patient belonged to age group 35-30 year as compared to 34%i patient who belong to age group more than >50 years. Mostly females were post-menopausal. It was also found that upto 80% had two or more than two risk factors. In conclusion, dyslipidaemia and Truncal obesity are important modifiable risk factors. These risk factors must he sought out in all high risk groups and where possible be treated for both primary as well as secondary prevention of CAD