effects of new polyherbal Unani formulation AJMAL06 on serum creatinine level in chronic renal failure

This study was conducted to evaluate the efficacy of Unani Ajmal06, an herbal formulation for management of chronic renal failure [CRF]. The therapeutic evaluations of three different formulations such as Itrifal Kashneezi, Jawarsih Zarooni Sada medicines were conducted on number 35 CRF patients clinically diagnosed cases of chronic kidney failure. It was found that herbal coded Ajmal06 was effective for the treatment of CRF in 70% of the patients treated. SPSS tests on sign and symptoms indicated the efficacy of Ajmal06 in lowering serum creatinine level in 70% of patients of chronic renal failure. In clinical response of BUN exhibited 75% of patients improved where as in case of fatigue [70%], edema [90%], leg pain [76%] improved these types of conditions with significant p value

Typhoid and non-typhoid ileal perforation: surgical experience of 50 cases

The objective of the study was, to find out the frequency of typhoid and non typhoid ileal perforation, to observe the association of various epidemiological factors in causation of disease and to note surgical, clinical, and laboratory findings along with mortality. A comparative descriptive study. The study was conducted in the department of surgery Civil Hospital Karachi from June 1997 to August 1998. fifty consecutive patients of non-traumatic ileal perforation managed surgically were observed by making two groups of typhoid and non typhoid ileal perforation. Out of 50 [n=50] 32 [Group - A] patients [26 male and 6 female] had typhoid while 18 [Group - B] patients [15 male and 3 female] had non-typhoid ileal perforation. There were 41 [82%] male and 09 [18%] female. In-group A age range was 16-50 years and a mean of +/- SD of 25 +/- 10 while in group B age range was 12- 60 years and a mean of +/- SD of 26 +/- 11.65. In group A 90.6% while in group B 100% patients had a single perforation. Wound infection was the most common complication. Mortality was 6.25% and 5.5% in group A and B respectively. There was no significant association [P<0.05] of gender, seasonal and living conditions. Surgical cum Epidemiological findings point out to the need of distinguish between different types of non traumatic ileal perforation, and having check on the related causative factors leading to their occurrences

Influence of anthropometric measures on age related cataract

To evaluate the Influence of Anthropometric measures on age related cataract. A cross-sectional study on local male population. This study was conducted in department of physiology basic medical science institute Jinnah post Graduate Medical Institute. [BMSI, JPMC] in collaboration with ophthalmology Department of JPMC and Physiology Department Dow Medical College Karachi. After selection of subjects by consecutive sampling, a prescribed proforma was filled. A complete eye examination was performed and the subjects were asked to attend the laboratory, after 12 hour fasting samples were collected. Serums were stored for analysis. Blood pressure was measured by mercury sphygmomanometer. Weight, Height, Body Mass Index, Waist Circumference, Hip circumference and Waist/Hip Ratio were recorded. Subjects were divided in to four groups. Group-A =Normotensive, Normoglycaemic with Cataract [as Control] Group-B=Hypertensive with Cataract Group-C=Diabetics with Cataract Group-D=Hypertensive, Diabetics with Cataract. This study revealed that age related Cataract is influenced by Anthropometric measures. In our population age related cataract is inversely influenced by body mass index in contrast to the developed countries