RESUMO
Objective: To determine the frequency of metabolic syndrome and its components in patients with carpal tunnel syndrome
Study Design: Case-series
Place and Duration of Study: Department of Neurology, Mayo Hospital, Lahore, from January to June 2012
Methodology: Seventy-five [64 females and 11 males] patients with clinically diagnosed and electrodiagnostically confirmed carpal tunnel syndrome were inducted. Their waist circumference, blood pressure, fasting blood glucose, fasting triglycerides and high density lipoprotein cholesterol levels were recorded. Patients were categorized having metabolic syndrome according to Adult Treatment Panel III criteria, if any 3 were present out of hypertension, elevated fasting triglycerides, reduced high density lipoprotein cholesterol, elevated fasting blood glucose, and elevated waist circumference
Results: Mean age of the patients was 42.04 +/- 9.31 years, mean waist circumference was 95.32 +/- 9.03 cm, mean systolic blood pressure was 134.13 +/- 13.72 mmHg, mean diastolic blood pressure was 89.13 +/- 8.83 mmHg, mean fasting blood glucose was 94.35 +/- 21.81 mg/dl, mean fasting triglycerides was 177.48 +/- 48.69 mg/dl, and mean high density lipoprotein cholesterol was 41.95 +/- 11.17 mg/dl. Metabolic syndrome was found in 54 [72%] patients including 9 [16.7%] males and 45 [83.3%] females. Out of 75 patients, 54 [72%] had elevated waist circumference, 52 [69.3%] had elevated blood pressure, 19 [25.3%] had elevated fasting blood glucose, 53 [70.6%] had elevated fasting triglycerides and 54 [72%] had reduced high density lipoprotein cholesterol. Highest frequency of metabolic syndrome was found in age range of 40 - 49 years in both genders
Conclusion: Metabolic syndrome is frequently found in the patients with carpal tunnel syndrome
RESUMO
To determine the outcome of treatment of microsurgical clipping in elderly [60 - 70 years] patients with aneurysmal subarachnoid hemorrhage and determine the predictors of poor outcome. Longitudinal analytical study. Nishtar Hospital, Multan, Mayo Hospital, Lahore, Department of Neurosurgery, Lahore General Hospital, Lahore, from January 2000 to January 2010. Elderly patients [60 - 70 years] with ruptured cerebral aneurysm were enrolled and graded on the basis of World Federation of Neurosurgeons Scale [WFNS]. Aneurysm sac obliteration was done in all the patients with microsurgical clipping. Postoperatively, the patients were assessed upto 3 months for outcome parameters i.e., neurological deterioration [based on WFNS grade and modified Rankin scale as favourable [mRS score <-2] and unfavourable [mRS score > 2]. The factors associated with unfavourable outcome were also noted which included age > 65 years, poor initial WFNS grade, and the occurrence of ischaemia. The mean age of the 48 patients was 65 +/- 5.45 years. There were 31 [64.6%] male and 17 [35.4%] female patients. Postprocedural neurological deterioration occurred in 23 patients [47.9%] related to ischaemia in 14 [29.16%], rebleeding in 1 [2%], and hydrocephalus in 8 [16.66%]. At 03 months, the outcome was favourable in 25 patients [52.08%] and unfavourable in 23 [47.91%]. In old patients, careful pre-operative assessment, interdisciplinary approach and meticulous tissue handling during aneurysm clipping may decrease the unfavourable outcome