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1.
Indian J Exp Biol ; 2007 May; 45(5): 455-8
Artigo em Inglês | IMSEAR | ID: sea-58629

RESUMO

The present study was aimed to find out whether a change in the alignment of the pyramid from the north-south axis causes any variation in the effects produced by it on plasma cortisol levels and markers of oxidative stress in erythrocytes of adult-female Wistar rats. Plasma cortisol and erythrocyte TBARS levels were significantly lower whereas erythrocyte GSH was significantly higher in rats kept in pyramid that was aligned on the four cardinal points--north, east, south and west, as compared to normal control rats. Although there was a significant difference in the plasma cortisol level between normal control group and the group of rats kept in randomly aligned pyramid, there was no significant difference between these two groups for the other parameters. Erythrocyte TBARS levels in the group of rats kept in the randomly aligned pyramid was significantly higher than that in the group kept in the magnetically aligned pyramid. The results suggest that the north-south alignment of the pyramid is crucial for its expected effects.


Assuntos
Animais , Egito , Eritrócitos/química , Feminino , Saúde , Abrigo para Animais , Hidrocortisona/sangue , Modelos Biológicos , Misticismo , Estresse Oxidativo/fisiologia , Ratos , Ratos Wistar , Substâncias Reativas com Ácido Tiobarbitúrico/análise
2.
Indian J Exp Biol ; 2006 Nov; 44(11): 902-4
Artigo em Inglês | IMSEAR | ID: sea-57499

RESUMO

Contribution and role of a pyramid/square box on the wound healing suppressant effect of dexamethasone was studied in rats of either sex using excision wound model to record the wound contraction rate and epithelization period. The results showed enhanced wound contraction rate and decreased epithelization period in the pyramid-exposed rats as compared to controls. Thus, it appears that pyramid environment facilitates the process of wound healing. Also, the wound healing suppressant effects of dexamethasone were significantly reduced.


Assuntos
Animais , Dexametasona/efeitos adversos , Meio Ambiente , Feminino , Masculino , Modelos Biológicos , Ratos , Ratos Wistar , Esteroides/efeitos adversos , Cicatrização/efeitos dos fármacos
3.
Indian J Exp Biol ; 2003 Nov; 41(11): 1289-93
Artigo em Inglês | IMSEAR | ID: sea-58204

RESUMO

The Giza pyramids of Egypt have been the subject of much research. Pyramid models with the same base to height ratio as of the Great Pyramid of Giza, when aligned on a true north-south axis, are believed to generate, transform and transmit energy. Research done with such pyramid models has shown that they induced greater relaxation in human subjects, promoted better wound healing in rats and afforded protection against stress-induced neurodegnerative changes in mice. The present study was done to assess the effects of housing Wistar rats within the pyramid on the status of oxidative damage and antioxidant defense in their erythrocytes and cortisol levels in their plasma. Rats were housed in cages under standard laboratory conditions. Cages were left in the open (normal control), under a wooden pyramid model (experimental rats) or in a cubical box of comparable dimensions (6 hr/day for 14 days). Erythrocyte malondialdehyde and plasma cortisol levels were significantly decreased in rats kept within the pyramid as compared to the normal control and those within the square box. Erythrocyte reduced glutathione levels, erythrocyte glutathione peroxidase and superoxide dismutase activities were significantly increased in the rats kept in the pyramid as compared to the other two groups. There was no significant difference in any of the parameters between the normal control and rats kept in the square box. The results showed that exposure of adult female Wistar rats to pyramid environment reduces stress oxidative stress and increases antioxidant defense in them.


Assuntos
Criação de Animais Domésticos , Animais , Antioxidantes/metabolismo , Egito , Eritrócitos/metabolismo , Feminino , Glutationa Peroxidase/metabolismo , Abrigo para Animais , Hidrocortisona/sangue , Malondialdeído/metabolismo , Misticismo , Estresse Oxidativo , Ratos , Ratos Wistar/fisiologia , Superóxido Dismutase/metabolismo
4.
Indian J Exp Biol ; 2003 Jun; 41(6): 645-8
Artigo em Inglês | IMSEAR | ID: sea-62266

RESUMO

With a view to investigate the contribution and role of environment within a wooden pyramid model on the wound healing suppressant effect of dexamethasone in rats, wound breaking strength, dry weight, hydroxyproline content and histology of granulation tissue of the dead space wound were studied in rats. The results indicate that the environment within the wooden pyramid not only promotes significant wound healing but also reduces the wound healing suppressant effect of dexamethasone. Histological studies also confirmed the results.


Assuntos
Animais , Dexametasona/farmacologia , Masculino , Ratos , Ratos Wistar , Cicatrização/efeitos dos fármacos
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