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No abstract available.
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No abstract available.
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We observed 285 cases of culture proved shigellosis from Jan. 1978 to July 1981 at W.M.B.H. in Busan. We specially observed the clinical and bacteriological response to Oxolinic acid in 59 cases from Jan. to July 1981. The following results were obtained. 1. The most commonly isolated shigella strains was Sh. flexneri (85.3%) followed by Sh. sonnei (7.4%), Sh. boydii (4.2%) and Sh. dysenteriae(3.2%). 2. Antibiotic sensitivity test revealed that more than 90% of strains were resistant to Tetracycline, Chloramphenicol and Ampicillin. Resistance strains to Gentamycin and Oxocid were found in less than 12.2% and 14.3% respectively. 3. The multiple antibiotic resistant strains were observed in about 80% of 59 strains, which were resistant to 3~5 antibiotics. The most of these strains were resistant to Ampicillin, Chloramphenicol and Tetracycline. In 3 cases it was resistant to all kinds of antibiotics but oxolinic acid. 4. Oxolinic acid showed growth-inhibitory zone of more than 11 mm with the concentration of 2mcg/ml in 95% and M.I.C. value of less than 0.76mcg/ml in 90%. 5. After administration of Oxolinic acid, there was clinical response within 2 days in 76.5% and conversion to negative stool culture within 2days in 68.8%. 6. Compared with placebo group, there was parallel clinical and bacteriologic effectiveness between Oxolinic acid and Rifampin.
Assuntos
Ampicilina , Antibacterianos , Asma , Cloranfenicol , Dermatite Atópica , Disenteria Bacilar , Gentamicinas , Ácido Oxolínico , Rifampina , Shigella , TetraciclinaRESUMO
We observed 285 cases of culture proved shigellosis from Jan. 1978 to July 1981 at W.M.B.H. in Busan. We specially observed the clinical and bacteriological response to Oxolinic acid in 59 cases from Jan. to July 1981. The following results were obtained. 1. The most commonly isolated shigella strains was Sh. flexneri (85.3%) followed by Sh. sonnei (7.4%), Sh. boydii (4.2%) and Sh. dysenteriae(3.2%). 2. Antibiotic sensitivity test revealed that more than 90% of strains were resistant to Tetracycline, Chloramphenicol and Ampicillin. Resistance strains to Gentamycin and Oxocid were found in less than 12.2% and 14.3% respectively. 3. The multiple antibiotic resistant strains were observed in about 80% of 59 strains, which were resistant to 3~5 antibiotics. The most of these strains were resistant to Ampicillin, Chloramphenicol and Tetracycline. In 3 cases it was resistant to all kinds of antibiotics but oxolinic acid. 4. Oxolinic acid showed growth-inhibitory zone of more than 11 mm with the concentration of 2mcg/ml in 95% and M.I.C. value of less than 0.76mcg/ml in 90%. 5. After administration of Oxolinic acid, there was clinical response within 2 days in 76.5% and conversion to negative stool culture within 2days in 68.8%. 6. Compared with placebo group, there was parallel clinical and bacteriologic effectiveness between Oxolinic acid and Rifampin.
Assuntos
Ampicilina , Antibacterianos , Asma , Cloranfenicol , Dermatite Atópica , Disenteria Bacilar , Gentamicinas , Ácido Oxolínico , Rifampina , Shigella , TetraciclinaRESUMO
We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief of the related literature was made on this subject.
Assuntos
Animais , Gatos , Pré-Escolar , Humanos , Masculino , Tosse , Diagnóstico , Dispneia , Teratoma , TóraxRESUMO
We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief review of the related literature was made on this subject.
Assuntos
Animais , Gatos , Pré-Escolar , Humanos , Masculino , Anemia , Tosse , Diagnóstico , Dispneia , Hemangioma , Síndrome de Kasabach-Merritt , Teratoma , Tórax , TrombocitopeniaRESUMO
Clinical and bacteriological studies were made on 168 cases of culture proved childhood shigellosis at Wallace Memorial Baptist Hospital in Busan between Aug. 1978 and July 1980. The following results were obtained. 1. Of 168 cases, 99 cases were male and 69 were female, the ratio being 1.4:1. The most frequently affected age group was between one three six years(57.7%) and the youngest was one month old infant(2 cases). 2. The peak incidence was in summer (34.5%), however it occurred throughout the year, even in winter(17.3%). 3. The most frequent symptoms on admission were diarrhea (86.9%), fever(77.4%), vomithing (36.9%), convulsion(38.7%) and abdominal pain(28.6%). 4. WBC count in peripheral blood was variable from leukocytosis to leukopenia and over 5% of band form was seen in 52.4%. 5. Sh. Flexneri was the most frequently isolated strain(86.3%) followed by Sh. Sonnei(6.5%), Sh. Boydii(4.8%) and Sh. Dysenteriae (2.4%). 6. The result of sensitivity test reveales that Oxolinic acid was the most sensitive drug(86.2%) followed by Gentamicin(83.9%) and Cefazolin(80.4%). It also revealed the high prevalence of resistance to Ampicillin(88.0%), Chloramphenicol(92.7%) and Tetracycline (95.6%). 7. 54 isolated shigellae strains were tested for Minimal Inhibitory Concentration in tube dilution method and inhibition zone diameter in single disc test (Rifampin disc 5g/ml). MIC were below 12.5g/ml in 77.7% and below 25g/ml in 90.7% and inhibition zone diameter was over 8mm in 88.7%. 8. Clinical response to antibiotic therapy revealed that clinical improvement was seen within 5 days of therapy in 48.1% of Ampicillin therapy group and 58.1% of Septrin therapy group and within 4 days of therapy in 95.7% of initial Rifampin therapy group and 97.2% of altrnative Rifampin therapy group. 9. Bacteriological response to antibiotic therapy revealed that within 4 days of Ampicillin and Septrin therapy the negative conversion rate was 49.1% and 54.4% respectively. The negative conversion within 3days of Rifampin therapy was observed in 93.4% of initial therapy group and 96.6% of alternative therapy group. 10. There was no untoward reaction of Rifampin during therapy except for the reddish discoloration of urine and stool.
Assuntos
Feminino , Humanos , Masculino , Ampicilina , Diarreia , Disenteria Bacilar , Incidência , Leucocitose , Leucopenia , Ácido Oxolínico , Prevalência , Protestantismo , Rifampina , Shigella , Tetraciclina , Combinação Trimetoprima e SulfametoxazolRESUMO
A case of Sturge-Weber disease in an 8 year old male was presented. The diagnosis was established by characteristic features of Sturge-Weber disease including facial portwine nevus, convulsion, right hemiplegia, intracranial calcification and mental retardation. A brief review of related literature was made.
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Criança , Humanos , Masculino , Diagnóstico , Hemiplegia , Deficiência Intelectual , Nevo , ConvulsõesRESUMO
The authors experienced a newborn infant of Osteogenesis imperfecta. Patient is characterized by multiple fracture of bone, blue sclera, and deformity of long bone. The review of literature was made briefly.
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Humanos , Recém-Nascido , Anormalidades Congênitas , Osteogênese Imperfeita , Osteogênese , EscleraRESUMO
A Case of congenital syphilitic nephrosis in 2 momth old female infant was presented with a brief reveiw of literature. The diagnosis was estabished by clinical, laboratory and X-ray findings, and her clinical response was excellent with penicillin therapy.
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Feminino , Humanos , Lactente , Diagnóstico , Nefrose , Síndrome Nefrótica , Penicilinas , Sífilis CongênitaRESUMO
A 2-month old female infant was admitted to the department of pediatrics because of abd ominal distension, failure to thrive & constipation, Paracentesis was done & revealed milkyyellowish fluid like chyle. The clinical symptoms, signs & laboratory findings were compatible with chylus ascites.
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Feminino , Humanos , Lactente , Ascite , Quilo , Constipação Intestinal , Insuficiência de Crescimento , Paracentese , PediatriaRESUMO
A full term nomal baby girl who born by C.S. due to C.P.D. had been done well until the age of 5 days when she suddenly developed vomiting & abdominal distension & became not doing well? Immediate abdominal X-ray revealed free air under the both diaphragm without gastric air bubble & air fluid level. Emergency operation was performed under the tentative diagnosis of stomach perforation & found a laceration, 6cm in length in the great curvature. She died 6 hrs after operation. We reported this case with a brief review of literature.
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Feminino , Humanos , Recém-Nascido , Diagnóstico , Diafragma , Emergências , Lacerações , Estômago , VômitoRESUMO
2 cases of fatal neurological complications following D.P.T. vaccination were presented with a brief review of literature. One case was a 6 mo. Old baby who developed symptoms 5 hrs. after his. 3rd D.P.T. inoculation and expired about 29 hrs. after vaccination. The other case was 5 mo. Old male who developed symptom 3 2/1 days after his 2nd D.P.T. incoulation and expired about 4 2/1 days after vaccination. The interesting findings in these 2 cases were hyperglycemia, severe acidosis, and hyperkalemia.
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Humanos , Masculino , Acidose , Hiperglicemia , Hiperpotassemia , VacinaçãoRESUMO
A 2,800gm of full term male baby was born to a 30 year old Gr. 3 multipara by pitocin induction under the diagnosis of fetal distress. At birth the baby was cyanotic and grunting and the heart rate was 50/min. The baby had been done poorly and died of congestive heart failure at the age of 33 hours. ECG revealed second degree heart block. Postmortem examination was permitted for the heart only which revealed Coarctation of Aorta, Persistent Truncus Arteiosus with Pulmonary Artery Stenos is and Single Ventricle.