[Management of pre-analytical nonconformities at the Microbiology Laboratory of CHU Ibn Rochd-Casablanca [between 2016 and 2018]]

The pre-analytical phase is one of the main sources of non-compliance [NC]. The objective of this work is to evaluate the NCs of the pre-analytical phase at the Microbiology laboratory of Ibn Rochd-Casablanca University Hospital, and to propose preventive solutions. It's a retrospective descriptive study that involved 2028 cases of pre-analytic NC seized over a period of 24-month [August 2016 -July 2018]. This study was based on the exploitation of the computerized data base of our laboratory. From 56143 analysis requests processed during the 24 months, 2028 [3,6%] cases of pre-analytical NC were reported. The most pronounced dysfunctions were noted the pediatric services [15%]. The control of the pre-analytical phase is an important point to reduce sampling nonconformities. The collaboration between the various actors [prescribers, samplers and biologists], the establishment of a NC file, a sampling guide, continuous training and staff awareness are needed to improve the quality of this step

Epidemiological profile of invasive bacterial diseases in children in Casablanca, Morocco: antimicrobial susceptibilities and serotype distribution

The aim of this prospective study in Morocco was to investigate the causes of invasive bacterial diseases in children in order to inform antibiotic therapy and vaccine choices. Of 238 children aged

[E. Coil K1, neonatal infection]

Between January 1988 and December 1991. A study about 10 cases of E. Coli K1 neonates infection was taken. This study find high data of mortality and morbidity. We assure that rapid diagnosis is an important test

Salmonella typhi meningitis. About one case

Authors report a case of salmonella typhi meningitis observed in the unity of intensive care of Casablanca Children Hospital. It is a rare affection with a dreadful prognostic especially occurring in infancy. Clinical, bacteriological aspects and the difficulty of treatment choice are reviewed

Escherichia Coli Ki neonatal meningitis

The authors report on a case of neonatal meningitis caused by a strain of E. coli K1. The interest of rapid technics for detection of bacterial antigens is emphasized and the place of third generation cephalosporins discussed

Epidemiological data on Listeria in Casablanca

Four strains of Listeria monocytogenes have been isolated from environnemental sources and feces from immunocompromised patients. These strains belong to the most frequent serotypes reported in human listeriosis, and are suceptible to various antibiotics

Serotypes and biotypes of Haemophilus influenzae responsible for meningitis. Report of an ampicillin resistent strain

Serotype b correspond to 99% of the strains of II. influenzae isolated in meningitis. The biotypes I and II are the most frequent. The authors report on the first betalactame producing strain isolated in Morocco

[Anti human T cell leukemia lymphoma virus [HTLV1] prevalence in a Moroccan population]

Epidemiological studies suggest African origin of retrouviruses of HTLV group [human T cell leukemia lymphoma virus] which are incriminated in the etiology of adult leukemia and acquired immunodeficiency syndrome [AIDS]. We have studied 610 sera of healthy subjects from different parts of Morocco. The prevalence of antibodies against HTLV[1] in this sample is weak [0,5%] similar of that shown in USA and Europe

[Diagnostic value of antibody coated bacteria in the site diagnosis of urinary tract injection]

The clinical and radiologic data cannot always differentiate between upper urinary tract and lower tract infections. The antibody coated bacteria test has been performed in 12 cases and has proved to be a sensitive and specific indicator of renal infection

Activity of 17 antibiotics on 500 strains isolated in Casablanca teaching hospital

Several antibiotics have been recently marketed in Morocco. The authors evaluate their respective interests, and bring practical propositions for their use

Value of determination of the aminoglycoside serum levels in severe infectious diseases

The authors have used a simple and cheap microbiological method for the determination of the aminoglycoside serum levels of four patients. The clinical situation where these monitoring may be useful are emphasized

Successful treatment of multiresistant klebsiella meningitis by cefotaxime

The authors report on the successful treatment of multiresistant klebsiella pneumoniae meningitis by cefotaxime. Because of their high antibacterial activity and their adequate diffusion into the cerebrospinal fluid, the "third generation cephalosporins" are suitable for treatment of gram negative meningitis

Rotavirus diarrhea in childhood in Casablanca

Rotavirus have been demonstrated in 17.6% of stools of 85 children suffering from acute diarrhea. The low incidence reported here can be explained by the season and by the age of the children

Monoclonal antibodies: principles, applications and future prospects

Monoclonal antibodies are produced by hydridomas of B lymphocytes and myelomatous cells. The number of monoclonal antibodies produced is still increasing. These antibodies are characterised by their absolute homogenicity and their high specificity. The aim of this study is to review the potential applications of these antibodies in the therapeutic and diagnostic fields

Bacteriological examination of urinary tract infections. the experience of a hospital laboratory

According to the data obtained from the second semester of 1983, the cytobacteriologic examinations of the urines represent one third of the total specimens received in the laboratory. 16.8% of the specimens analysed show a significant bacteriuria. The distribution of the bacteria and their antibiotic suceptibility are discussed

Treatment of urinary tract infections

Antibiotic treatment of urinary tract infections is based upon natural history and clinical signs of the infection. The epidemiological, the bacteriological and pharmacological data are reviewed and the treatment of the major clinical situations is discussed

Treatment of urinary tract infection with a daily and unique dose of gentamycin

Twenty nine patients with Gram negative urinary tract infection have received gentamicin in a single daily dose of 2,5 mg per kilogram of body weight for 10 days. Follow up is based on bacteriologic and biologic data and on dosage of gentamicin. The mean values of gentamicin levels obtained in blood and urine are efficient and non toxic. In 14% of cases, failure of treatment is due to a local cause of urinary tract infection. A single daily dose of gentamicin is efficient and non toxic if adapted to the patient's weight