[Nasopharengial angiofibroma in the oral cavity in a 50-year-old man: a case report]

The angiofibroma is a rare benign vascular tumor that often occurs in the nasopharyn and paranasal sinuses in male adolescents. Presentation of this lesion in the oral cavity is very rare. This paper presents the case of a-50-year old male with an angiofibroma on the buccal mucus as exophytic lesion with red-brown color which had grown during 8 years. Based on the clinical findings, working diagnosis was mesenchymal tumor. After excisional biopsy, histopathologic feature proved to be angiofibroma

[Evaluation of eosinophilic infiltration in oral squamous cell carcinoma and its correlation with cervical lymph node metastasis and histological grading]

Eosinophils are suggested to have had participated in neoplastic invasion and metastasis. The aim of the present study was to evaluate eosinophilic infiltration in oral squamous cell carcinoma [OSCC] and assess its correlation with cervical lymph node metastasis and histological grading. This cross-sectional study used 20 OSCCs samples with lymph node metastasis and 20 samples without [NLM] were selected from the files of Tehran Cancer Institute. Hematoxylin-eosin stained sections were used to evaluate the presence of eosinophils in neoplastic tissues and OSCCs grading. Eosinophils were counted in 10 dense- and 10 classic-high-power-fields and graded from 0 to 4. Statistical analysis as well as Mann-Whitney-U and Kruskal-Wallis tests. The largest percentage of cases in OSCCs with and without LNM based on Eosinophil grading was 50% in grade 1 and 70% in grade 2, based on the dense-field count; and 50% in grades 1 and 0 and 70% in grade 1, when using the classic-field counting method, respectively. Eosinophilic infiltration was not significantly different between the two groups [P>0.05]. A significant difference in mean Eosinophilic count was observed among the histological grades when using the dense-field method [P=0.004], but not the classic technique [P=0.029]. Within limitations of present study it appears that the presence of Eosinophils in OSCC specimens could not be used as a clinical predictor for lymph node metastasis, however further investigation with a larger sample size is required to clarify the role of these inflammatory cells in OSCC cases

[ 31-year-old statistical survey on growth - development odontogenic cysts in pathology department, faculty of dentistry, Tehran University of medical sciences]

Aim and Background: odontogenic cysts are known as real cysts covered with an epithelium originated from "Odontogenic epithelium". These cysts make up a wide range of oral and maxillofacial pathologic lesions that may acquire an aggressive nature and afflict a vast region of jaws. Despite considerable prevalence, a few studies have been already conducted on these lesions in Iran. The purpose of this descriptive and archive review study was to survey statistically odontogenic cysts of growth-developmental origin

Materials and Methods: in order to perform this study, the archive of pathology department dental Faculty Tehran University of Medical Sciences were reviewed from 1971 to 2002. In addition to survey the prevalence of all odontogenic cysts of growth-developmental origin, information on factors such as age, sex and location of lesion were also extracted from archive files and analyzed by SPSS software program

Results: the findings of this study indicated that out of all reviewed files, 736 odontogenic cysts of growth-developmental origin were found including: dentigerouse cyst [51%], odontogenic keratocyst [36%] Gorlincyst [6%], primordial cyst [3%], lateral periodontal cyst [2%], eruptive cyst [1%] and adult gingival cyst [1%]. No sample of infant gingival cysts were observed. Totally, 198 cases [28%] occurred in the second decade of life more than other decades. 63% and 37% of such cysts were reported in males and females, respectively. Considering the location of lesion, 61% and 39% of them were found in the lower and upper jaws, respectively. in the lower jaw: 46% in molar, 31% in premolar, 23% in the interior regions were observed and in the upper jaw 47% of cases in the anterior region, 28% and 25% in premolar and molar regions were found, respectively

Conclusion: according to the present study, 39% of all jaw cysts existing in pathology department archive are of odontogenic type with growth-developmental origin, out of them dentigerouse and keratocyst ones make up the largest number

Chondrosarcoma, a 30 year retrospective study in cancer institute Imam Khomeini hospital and faculty of dentistry of Tehran university of medical sciences

Statement of Problem: Chondrosarcoma is a tumor which includes 10 percent of the bone primary tumors. Its prevalence is half of the osteosarcoma and two times of Ewing's. The mean age of the patients ranges between 30-50 years of old. There is no significant sex or race predilection. The most common complaint is the presence of a painless and enlarging mass. Its clinical course is described as slow-growing lesion with local invasion and recurrence, no or delayed metastasis, almost long survival

Purpose: The aims of this study were as follows: the determination of prevalence of reported Chondrosarcoma in cancer institute Imam Khomeini hospital and faculty of dentistry of Tehran University of medical sciences, comparison of jaw Chondrosarcoma to the body one, evaluation of sex, age, clinical and histological parameters and prevalence of different locations in body

Materials and Methods: In this study the biopsy notes of all kinds of chondrosarcoma of the body in cancer institute [212 cases] and the extracted files of the patients with the jaws chondrosarcoma in cancer institute and department of oral pathology of faculty of dentistry, University of Tehran medical sciences [23 Cases] were evaluated

Results: In this retrospective statistical study the proportion of the patients with the jaws conventional chondrosarcoma to the patients with conventional Chondrosarcoma of the body was 8.57%. The mean age of the total patients and the patients with jaws chondrosarcoma were 36.21 and 38.87 years, respectively. Men were somehow more involved. Pelvic was the most common location of the tumor. Maxilla involvement was 3-4 times more than mandible. Microscopic manifestation and tumor grading suggested a low grade lesion in jaws. Local recurrence in jaws was 33.3%

Conclusion: The most common site of involvement of chondrosarcoma was pelvic and maxillary involvement was more common than mandible. Its prevalence was in the posterior site of the jaws