Effect of some drugs on the peritoneal membrane in resistant ascites of schistosomal origin

The influence of some drugs on the ascitic fiuid-plasma barrier was studied in 10 schistosomal patients suffering from resistant ascites. Fibrinolysin, dexamethazone, heparin, and Vitamin B complex, were able to improve transmission through such a barrier with the possible corection of some factors that lead to resistancy of ascites as hypoalbuminaemia, hypo-natraemia, and hypovolaemia. Intraascitic injection of such drugs with mersalyl caused diuresis. The present study gives a further evidence that the barrier is biologically active