Rosai-Dorfman disease with pleural involvement

Sinus histocytosis with massive lymphadenopathy [SHLM] disease is considered to be indolent with self limiting pathology. However, severe morbidity and mortality have been attributed to complications of SHLM. Lower respiratory tract involvement, which is often unfavorable, is rarely reported and carries particularly grave prognosis. A case of sinus histocytosis with massive lymphadenopathy [SHLM] is reportedhere. The patient had lower respiratory and pleural involvement

[Association of Castleman's disease and Hodgkin lymphoma a case report]

Castelman's disease is an atypical lymphoid proliferation presenting in two different types [localized or multicentric]. The localized form has a better prognosis and a surgical treatment may confer a long remission. Authors report the case of a 43-years-old man who consulted for distal arthralgia and cervical lymphadenopathies. Cervical neck dissection permits a clinical remission during 4 years. The patient reconsulted in 2004 for cervical, axillary and medastinal nodes. Biopsy concluded to an association of Castelman disease and Hodgkin Lymphoma in its nodular sclerosis form. The patient was successfully treated with chimiotherapy. Two years later, he remains asymptomatic with no sign of relapse

[Testicular plasmocytoma: a case report]

Extramedullary plasmocytoma is rare, with less than 50 reported cases and only 8 cases of primary testicular plasmocytoma. Report of a new case. This report concerns a 65 years old patient presenting an enlargement of the testis. The diagnosis of testicular plasmocytoma was made on histological examination. There was no evidence of bone marrow involvement or systemic signs of myeloma. This case will be studied with a review of the literature

[New advances in the management of gastric marginal zone B cell lymphoma]

The stomach is the most common site involved in primary gastrointestinal lymphoma. Helicobacter pylon [HP] plays a decisive role in the pathogenesis of gastric marginal zone B cell lymphoma of mucosa associated lymphoid tissue. Eradication therapy has become widely accepted as initial treatment of localized low grade MALT lymphoma. Further studies are needed to determine the most adapted treatment in non-responding patients. A long-term endoscopic follow-up is recommended due to the increased risk of gastric adenocarcinoma in spite of Helicobacter pylon eradication

[Dermatofibrosarcoma protuberans about 18 cases]

Dermatofibrosarcoma protuberans [DFSP] is a rare mesenchyma skin tumor. It is characterized by a slow growth with a high rate of recurrence but limited potential for metastasis. We report the result of a retrospective study of 18 cases of DFSP collected over 16 years in the dermatology department of La Rabta Hospital. The mean age was 32 years with a sex ratio of 1.57. The site of predilection was the trunk [77.5%]. Histological features were typical in all cases with positivity for CD34 in 14 cases. Treatment was surgical in 13 cases. DFSP is a tumor of intermediate malignancy, which can have aggressive course. This tumor is best treated with surgery in which large excision are necessary to reduce the risk of recurrence

[Neuroendocrine tumours of the pancreas - a report of two cases]

Neuro-endocrine tumors of the pancreas are rare. Tumors can be discovered according to the endocrine syndrome produced. They are characterised by a slow evolution. Criteria of malignancy are metastasis to lymph node, liver or dissemination to other organs. Occurrence of multiple neuro-endocrine tumors may be seen forming multiple endocrine neoplasie type 1 or MEN-1

L'adenocarcinome de l'appendice - a propos de deux cas

Primary adenocarcinoma of the appendix is rare, account for about 1% of all digestive tract carcinoma. The prognosis varies with grade of malignancy and the Dukes classification. For this reason, simple appendicectomic is sufficient treatment, and it is justifiable for perform rigth hemicolectomic when the carcinoma spread across the line of the muscularis mucosae into the submucosal layer, because the risk of lymph node metastasis