RESUMO
To compare anterior segment and ocular biometric parameters of unaffected fellow eyes of patients with a previous attack of acute angle closure [AAC], primary angle closure suspect [PACS] eyes, and normal eyes; and to assess the risk of developing AAC in PACS. In this prospective comparative observational case series, 16 unaffected fellow eyes of patients with a previous attack of AAC [group I], 40 PACS eyes [group II] and 32 normal eyes [group III] were evaluated. Pentacam and A-scan echography were performed in all cases. Anterior chamber angle [ACA], anterior chamber volume [ACV], anterior chamber depth [ACD], central corneal thickness [CCT], keratometry [KR], lens thickness [LT] and axial length [AL] were measured in all eyes as main outcome measures. Age, CCT and LT were comparable among the study groups [all P values>0.05]. Mean ACA was 24.8, 22.9 and 35.4 in groups I, II, and III respectively [P<0.001]. Corresponding values for ACV were 72, 76 and 172 microl, respectively [P<0.001]. Central ACD measured from the endothelium was 1.80, 1.91, and 3.09 mm in groups I, II, and III respectively [P<0.001]. Using receiver operating characteristic [ROC] curves, ACV=100 microl was associated with a high risk of AAC with sensitivity of 91.7% [95% Confidence Interval [CI]:70 to 99] and specificity of 100% [95% CI: 89 to 100]. Corresponding values for ACA=25 were 75% [95% CI: 51 to 90] and 93.3% [95% CI: 79 to 98]; and for ACD=2.1 mm were 86.7% [95% CI: 62 to 96] and 100% [95% CI: 89 to 100] respectively. If two of these three criteria [ACV=100 microl, ACA=25 and ACD=2.1 mm] are present, the eye can be considered at high risk for an attack of AAC with sensitivity of 93.3% [95% CI: 70 to 99] and specificity of 100% [95% CI: 89 to 100]. Eyes with ACV=100 microl, ACA=25 and ACD=2.1 mm should be considered at high risk for developing acute angle closure and can be considered for prophylactic laser peripheral iridotomy [LPI]
RESUMO
To compare the efficacy and safety of topical Mitomycin-C [MMC] drops versus subconjunctival 5-Fluourouracil [5-FU] injections for management of early bleb failure after trabeculectomy or combined phacoemulsification and trabeculectomy with posterior chamber intraocular lens implantation [PT+PCIOL]. In a comparative study, 37 eyes of 37 patients with impending early bleb failure were randomly allocated to MMC 0.02% eye drops [19 eyes] or subconjunctival 5-FU injections [5mg each dose] [18 eyes] for 2 to 4 weeks or. Main outcome measures included intraocular pressure [IOP], and bleb morphology according to the Indiana Bleb Appearance Grading Scale. Other outcome measures included success rate, number of glaucoma medications, best corrected visual acuity [BCVA] and complications. Complete success was defined as 5
RESUMO
To evaluate the effect of early drainage of delayed suprachoroidal hemorrhage [SCH] after glaucoma surgery. These study reports seven cases of delayed supra-choroidal hemorrhage following glaucoma surgery managed with early drainage. In this series instead of waiting for 7 to 14 days for clot lysis, the SCH was drained from the suprachoroidal space immediately after diagnosis. Seven eyes of 7 patients with delayed SCH including 4 men and 3 women were enrolled in the study. Median age was 42.57 +/- 29.61 years and mean follow up duration was 21.43 +/- 13.35 months. Immediately after diagnosis, choroidal tap and anterior chamber reformation were performed for all the patients. Intraocular pressure [IOP] decreased significantly after intervention. At final follow up, mean visual acuity was 1.08 +/- 0.31 LogMAR. Immediate surgical drainage of suprachoroidal hemorrhage seems to be an effective and safe method for treatment of delayed SCH; and it may decrease the inflammation from the entrapped blood in suprachoroidal space and reduce complications and additional procedures. Larger trials are recommended for further evaluation