case report of primary localized amyloidosis of eyelid with extensive calcification and ossification, clinically presenting as a bone tumor

Primary localized amyloidosis of eyelid is a localized type of amyloidosis without evidence of systemic involvement. We report a 75-year-old man suffering of unilateral [left] ptosis due to upper eyelid mass with bony consistency. Eye examination revealed upper lid mass attached to tarsus. No ocular infection or inflammation was found. Pathologist reported diffuse distribution of eosinophilic homogenous deposits of stroma that show apple green birefringence by polarized light compatible with amyloidosis. Primary localized amyloidosis may appear as a bony tumoral mass. It is important to consider secondary localized and systemic amyloidosis in differential diagnosis of the disease

Serum alpha 1-antitrypsin level in patients with atrophic rhinitis

Serum alpha 1 antitrypsin [AIAT] level was determined in twenty four patients with primary atrophic rhinitis. It was found that serum alpha 1- antitrypsin levels were significantly lower in patients with primary atrophic rhinitis, while there was no change in patients with secondary atrophic rhinitis. We may conclude that AIAT deficiency is an aetiological factor of the primary atrophic rhinitis, and its determination may help to understand its pathogenesis and to differentiate it from secondary types