Estimation of total IgE in the lacrimal fluid and serum of patients with giant papillary conjunctivitis

Total IgE levels in the lacrimal fluid and serum were estimated in 28 soft contact lens wearers having giant papillary conjunctivitis [GPC] and in 22 normal soft contact lens wearers using the paper radioimmunosorbent test [PRIST]. A considerable elevaltion of lacrimal and serum IgE was detected in 24 [85.71%] out of 28 GPC patients The elevation was more pronounced in lacrimal than in serum IgE A slight elevation was detected in only 3 [13.63%] out of the 22 normal contact lens wearers