effect of 6 weeks swimming and consumption of zingiber officinale roscoe extract on some inflammatory and anti-inflammatory factors in heart tissue of mice induced by breast cancer

Back ground: Heart disease is one of the side effects of breast cancer. Physical activity and herbs are effective in reducing the inflammatory factors of the heart tissue

Objective: The purpose of this study was to evaluate the effect of 6 weeks of swimming and ginger on some inflammatory factors of the heart tissue of mice induced by breast cancer

Methods: 60 female Balb C-female [6-8 weeks old] and [150-250 g weight] after induction of breast cancer [surgical technique] and familiarity with the environment were randomly divided into 6 groups: healthy control, control Cancer, Cancer-Swim, Cancer-Supplement, Cancer-Saline-Supplement and Cancer-Saline. Swimming and swimming-Supplement groups swam for 6 weeks, five days a week and 60 minutes a day. Supplements and supplements-swimming groups were injected 6 days a day with ginger extract [20 mg / kg] and saline [sodium chloride 0.9%]. After intervention, alpha-Tumor necrosis levels [TNFa] and Interleukin10 [IL10] were measured by ELISA and specialized kits. One-way analysis of variance was used to analyze the data [P <0.05]

Results: The results showed that induction of cancer was associated with an increase in TNFa and a decrease in IL10. Six weeks of swimming, supplementation and combined intervention reversed these changes. But there is no significant difference between these three independent variables

Conclusion: Swimming, supplementation of ginger and their combination may be effective in modulating inflammatory and anti-inflammatory factors in the heart tissue of breast cancer patients

[Impact of diabetes, hyperlipidemia, smoking and other risk factors on survival time of the elderly participants in the Tehran lipid and glucose study. a 10-year follow-up]

Introduction: In the rapidly increasing elderly population of Iran, no prospective health studies have yet been undertaken. This study was conducted to identify the risk factors of survival time of elderly Tehranians, aged above 60 years

Materials and Methods: Individuals aged above 60 years old [n=929], recruited in the primary phase [1998-2001] of the ongoing Tehran Lipid and Glucose Study [TLGS], were followed up for 10 years and their vital statistics were documented [1998-2008]. Age and sex mortality rates for age groups [60-69, 70-79, 80+] were calculated and the hazard rates were estimated using Cox proportional hazard model

Results: Of 929 males, 154 [17%] and out of 869 women 85[10%] died during the follow-up years. Cox model showed that diabetes, on an average, reduced 2.5 years and 4.4 years, while smoking reduced 6.6 and 5 years of females' and males' survival time, respectively. BMI>33Kg/m2 and dyslipoproteinemia reduced 4.5 years and 4 years of women's life spans, respectively. Native Tehranian males on an average, live 3 years less than other male residents; in addition, hypertension and history of MI, stroke or sudden death of father, brother or son reduced 3.3 years and 4.1 years of men's life time respectivly

Conclusion: Elderly women with BMI>33 Kg/m2 and/or smokers and/or with dyslipoproteinemia are more in need of health care, while among their male countery parts elderly diabetic men and/or smokers and/or those who have history of MI, stroke or sudden death of a father, brother or son also need more attention

[Assessment of some factors related to leave in nurses and their demographic characters in educational hospitals of Shahid Beheshti university of medical sciences]

Nurses are the largest group of health care professionals in health systems. Nurse's shortage and turnover lead to big problems in care of patients, quality of care and treatment costs. The aim of this study was to determine assessment of some factors related to leave in nurses and their demographic information in educational hospitals of Shahid Beheshti University of Medical Sciences In this, descriptive-correlative study, 350 nurses were randomly selected. Personal demographic questionnaire [11 items] and Anticipated Turnover Scale [ATS] [12 items] were used to collect data. Content validity index and reliability were measured by internal consistency [alpha=0/80] and test- retest[r=0/81]. Samples of 12 teaching hospitals and in different shifts were selected and questionnaires were distributed and collected at nurses rest time. Data was analyzed by SPSS-16. Results showed that 88 percent of nurses were women and 92 percent had a bachelor's degree. Also they age range was between 57-23 and 48 /3 percent of them worked in medicalsurgical ward. Results indicated that nurses had a moderate intent to leave their work. In addition, between age with intent to leave [r= - 0/114] and work experience[r= - 0/158] with turnover, was a negative significant correlation. In addition, there was a significant correlation between organizational level and intent to leave [P= 0/007], shift and intent to leave [P = 0/001]. Given the high turnover of Iranian nurses than similar studies in abroad and according to previous research that showed a direct relationship between intent to leave and the actual turnover of nurses, need more attention