[Effect of varnish fluoride on prevention of baby bottle tooth decay in 12- 36 months-old babies]

The baby bottle tooth decay is a prevalent type of caries, affecting most of the teeth in deciduous dentition, and it is mostly caused by overnight bottle feeding. Given the importance of implementing preventive procedures, the aim of this study was to determine the effect of varnish fluoride on prevention of baby bottle tooth decay in deciduous dentition. This experimental study was carried out on 52 kindergarten children aged one to three years-old in Tehran. The right maxillary centrals and laterals were considered as cases and the left counterparts as control group. Bifluoride-12 varnish [Voco, Germany] was applied twice over a 6 months period on the buccal and palatal surfaces of 104 case teeth. The results were compared with equal number of control teeth. Cochran-Q, Chi-square and Fisher's exact tests were used for data analysis. After fluoride therapy, 3 [5.77%], 11 [21.16%], and 8 [15.38%] teeth developed new caries in laterals of case groups, centrals and laterals of control groups respectively. None of the centrals in the case group developed new caries. The observed group differences were statistically significant [P<0.001]. According to Chi-square and Fisher's exact tests, factors such as patients' age, gender, geographic region, nutrition habits, oral hygiene and antibiotic consumption had no effect on caries prevalence [P>0.05]. According to the findings of this study, it can be concluded that, fluoride varnish may be considered as effective preventive procedure in nursing bottle caries reduction in children with primary dentition

[ immunohistochemical study of S-100 protein in salivary gland tumors: pleomorphic adenoma [PA], adenoid cystic carcinoma [ACC] and mucoepidermoid carcinoma [MEC]]

Salivary gland tumors comprises a large groupe of oral cavity lesions. Ductal and myoepithelial cells are introduced as original cells in salivary gland tumors. The histogenesis of salivary gland tumors are controversial. With considering the role of s-100 protein in demonstration of myoepithelial cells, the purpose of this study was the determination of immunoreactivity pattern and distribution of myoepithelial cells in PA, ACC and MEC. Formalin- fixed paraffin- embedded from 5 PAs, 5 ACCs and 5 MECs were studied immunohistochemically with employing S-100 protein. The S-100 protein positive cells were counted and mean score of Labeling Index [LI] were achieved. The immunoreactivity and staining pattern of each tumor were stablished .Lack of bleeding and necrosis was considered as inclusion criteria. 1] In PA: The plasmacytoid and some of ductal cells were stained positive [LI=0.34].The immunostaining reaction was moderate to severe. 2] In ACC: S-100 protein Immunoreactivity was negative [LI=0]. 3] In MEC: The small numbers of epithelial cells were stained. Since, the stained epithelial cells was lesser than 5%, the MECs was considered negative. Based on this study, the myoepithelial cells do not comprises the main cellular part in ACC and MEC