RESUMO
Chronic arsenic toxicity has been recognized as a typical form of arsenicosis which is defined by the experts of International Health Organization as a chronic health condition arising from prolonged ingestion of arsenic above the safe dose for at least six months, usually manifested by characteristic skin lesions of melanosis and keratosis, occurring alone or in combination, with or without the involvement of internal organs The present study evidences that the occurrence of skin manifestation varies form pigmentary changes, progressing to keratosis and even may lead to malignancy. The findings obtained obviously illustrate interlink between dynamics of severity of anemia and the promotion of the viable development of dermatological grading of arsenicosis