RESUMO
Actinic keratosis (AK) is a common, sun-induced, pre-malignant lesion with a strong likelihood of progressing to a malignancy. The reported risk of AK progressing to squamous cell carcinoma (SCC) varies from less than 1% to 20%. Clinically, induration, pain, large size, marked hyperkeratosis, ulceration, bleeding, rapid growth, and recurrence or persistence may be markers of AK progression into SCC. The risk of SCC metastasizing ranges between 0.5% and 3%. However, SCC of the lip arising from actinic cheilitis is more prone to metastasis than cutaneous SCC, with rates of the former varying between 3% and 20%. Here we report a typical case of SCC from actinic cheilitis with metastasis to the lymph nodes during a 4-year follow-up period. To exclude SCC, we emphasize the need for regular follow-up and prompt evaluation, including careful pathologic examination for actinic cheilitis.
Assuntos
Actinas , Carcinoma de Células Escamosas , Queilite , Seguimentos , Hemorragia , Ceratose Actínica , Lábio , Linfonodos , Metástase Neoplásica , Recidiva , ÚlceraRESUMO
Glomus tumor is composed of a benign neoplasm arising from the glomus body, which participates in thermal regulation. It usually presents as a circumscribed or solitary tumor characterized by paroxysmal pain. They are generally located in the distal extremities, and are most frequently present in the palms, soles, or nail beds. The author herein reports a case in which a glomus tumor was discovered in the nose. A glomus tumorin the nose is rare. In this case, a 66-year-old woman had a solitary, tender, bluish subcutaneous nodule with superficial telangiectasia on her nose for 20 years.
Assuntos
Idoso , Feminino , Humanos , Extremidades , Tumor Glômico , Unhas , Nariz , TelangiectasiaRESUMO
BACKGROUND: Idiopathic calcinosis cutis (CC) is currently sub-classified as tumoral CC, sub-epidermal calcified nodules, idiopathic CC of the scrotum, and milia-like CC. This sub-classification system is obscure and can be confusing at times. OBJECTIVE: This study was designed to characterize the clinical and histologic features of idiopathic CC, to evaluate the adequacy of the current sub-classification system, and to propose a new sub-classification system. METHODS: Thirty patients with idiopathic CC were sub-classified according to the Lever classification and the Walsh and Fairley classification and were also categorized based on the type of the primary lesion. RESULTS: Idiopathic CC lesions were most common on the buttock (n=7), followed by the scrotum (n=5), arms and legs (n=5), hands and feet (n=4), inguinal area (n=3), ears (n=2), neck (n=2), trunk (n=1), and face (n=1). With the Lever classification, twenty-three of 30 cases were categorized as "unclassified". With the Walsh and Fairley classification, twenty-three cases were categorized as "unclassified", whereas with our new classification system, we managed to classify all cases as either nodular or papular calcification according to the type of the primary lesion. CONCLUSION: In this study, we identified a common location and the primary morphological features of idiopathic CC. Our findings suggest that our new sub-classification system based on the type of the primary lesion would be useful.
Assuntos
Humanos , Braço , Nádegas , Calcinose , Orelha , Pé , Mãos , Perna (Membro) , Pescoço , EscrotoRESUMO
Dominant dystrophic epidermolysis bullosa-pretibial (DDEB-Pt) is an extremely rare subtype of dominant dystrophic epidermolysis bullosa (DDEB). Clinically, DDEB-Pt is characterized by trauma-induced blistering with scarring that predominantly affects the pretibial region and causes nail dystrophy. A 42-year-old woman had recurrent numerous pruritic lichenoid papules and plaques and a few vesicles on both the pretibial areas with toenail dystrophy for over 30 years. Her son and daughter also had the same lesions on their pretibial areas with associated dystrophic toe nails. Herein we report on a case of DDEB-Pt occurring in one family as a rare case.
Assuntos
Adulto , Feminino , Humanos , Vesícula , Cicatriz , Epidermólise Bolhosa , Epidermólise Bolhosa Distrófica , Unhas , Núcleo Familiar , Dedos do PéRESUMO
Angiokeratomas represent vascular lesions and are histologically characterized by superficial vascular ectasia and overlying acanthosis and/or hyperkeratosis. Angiokeratomas can be classified into five types, with angiokeratoma circumscriptum representing the least common of the five types. Angiokeratoma circumscriptum presents at birth and frequently occurs unilaterally on the leg. Herein, we report a rare case of long term angiokeratoma circumscriptum (twelve years) on the right chest, discovered following the excision of a lipoma from the same area.