Oral cytomorphometry of smokers and non smokers

The objective of the study was to observe and compare the changes in buccal exfoliated cells between smokers and Nonsmokers. Cross sectional comparative study. Study was carried out at Islamic International Dental College, Islamabad and Post Graduate Medical Institute, Lahore. The duration of study was six months i.e 1st September 2013-lst March 2014. Convinient, non-probability sampling technique was used. Quantitative data was obtained. The study groups consisted of 66 subjects divided into two equal groups of smokers S and non- smokers M, of ages between 15yrs-60yrs. Cellular diameter CD, nuclear diameter ND and nuclear to cytoplasmic ratio N/C ratio was assessed in buccal mucosal smears taken from clinically normal mucosa of smokers and normal subjects using exfoliative cytology. SPSS version 17.0 was used for data entry and statistical analysis. ANOVA and post-hoc tuckey were used for statistical analysis. The mean cellular diameter of smokers and non-smokers was 54.41 +/- 3.30pim and 43.81 +/- 2.01pim respectively. The mean nuclear diameter of smokers and non-smokers was 12.68 +/- 0.90

Need to revise oral pathology curriculum

Oral pathology is one of the major basic dental science subject taught to 3rd Year BDS students. Like other basic dental science subjects, oral pathology is gradually emerging as specialty in Pakistan as more students pursue post-graduation opportunities both nationally and internationally. Graduate students are trained according to standard outlines directed at familiarizing them to the pathologies of the oral cavity. However, at the undergraduate level the current oral pathology curriculum currently taught in Pakistan Dental College is quite vague and needs thorough revision. The aim of this article is to make some suggestions for the improvement of the oral pathology curriculum with emphasis on geographical variations of oral diseases worldwide

Cytomorphometry of buccal smears of Nicotiana tabacum [naswar] users: a pilot study

The objective of the current study was to asses the cytomporphometric changes in buccal mucosal smears of naswar users. The study groups consisted of 24 subjects divided into two groups i.e A control group and B naswar users of ages between 15yrs-60yrs. Cellular diameter CD, nuclear diameter ND and nuclear to cytoplasmic ratio N/C ratio was assessed in buccal mucosal smears taken from clinically normal mucosa of naswar users and normal subjects using exfoliative cytology. The mean cellular diameter of group A and B was 43.93microm and 44.13microm respectively. The mean nuclear diameter of control group and naswar users was 9.99microm and 11.88microm respectively. And the mean N/C ratio of group A and B was 1: 4.42 and 1: 3.71 respectively. The independent T test showed significant results [p

Malignant tumors of the minor salivary glands in northern Pakistan: a clinicopathological study

Malignant tumors of the minor salivary glands comprise a small but significant proportion of oral cancers. We analyzed this group of tumors in our population. The records of all cases of malignant minor salivary gland tumors diagnosed at the Armed Forces Institute of Pathology [AFIP], Rawalpindi, Pakistan, during a period of 10 years [1994-2003] are described. The institute receives biopsy material from armed forces and public and private sector hospitals in northern Pakistan as well as referrals for second opinion. A total of 21168 tumors were recorded at the AFIP Tumor Registry during the study period. These included 70 malignant minor salivary gland tumors. Twenty-three of these [32.8%] arose in the palate while the remaining tumors originated at other sites in the oral cavity. The commonest histological type was adenoid cystic carcinoma, constituting 30 cases [42.8%]. The next most common type was mucoepidermoid carcinoma; comprising 26 [37.1%] cases. The mean age of cases was 43.4 years and the male-to-female ratio was 1:1.4 There were 2 cases each of polymorphous low-grade adenocarcinoma and clear cell adenocarcinoma. The remaining cases included undifferentiated carcinomas, adenocarcinomas [not otherwise specified] and a few other rare tumors. Adenoid cystic carcinoma was the commonest malignant neoplasm of the minor salivary gland followed by mucoepidermoid carcinoma. The palate was the commonest location of these tumors