RESUMO
Objective: Exercise activity could be an amendment to polycystic ovary syndrome [PCOS]. However the acute and chronic effects of various exercise intensities on serum leptin levels are ambiguous. This study investigates the acute and chronic responses of various intensities of exercise on serum leptin levels and weights of female rats with PCOS
Methods: In this semi-empirical study, 80 adult Wistar rats [185 +/- 22 gr] after PCOS induction were divided into two groups. Group 1 participated in an exercise program at an intensity of 50%-55% maximal oxygen consumption [20 m/min], 70%-75% maximal oxygen consumption [28 m/min] and 80%-85% maximal oxygen consumption [34 m/min]. Group 2 participated in an eight-week training program, three days a week for 60 minutes. One-way analysis of variance test [ANOVA] was used to compare differences between groups. Significance was p<0.05
Results: In the acute training group, there was no change in weight in the sub-groups of group 1. In group 2, training reduced in the medium intensity 2 compared to the PCOS control 2 groups. Serum leptin levels did not respond to one session of exercise at various intensities in group 1 subgroups. Leptin levels significantly reduced in the medium intensity 2 group compared to the PCOS control 2 [p=0.044] group
Conclusion: One exercise session does not seem to significantly affect serum leptin levels. Exercise training at medium intensity probably can reduce leptin levels and weight in subjects as a non-pharmaceutical alternative in PCOS patients