Role of Uterine Artery Doppler in 11-14 Weeks Scan as a Predictor of Preeclampsia

Background: Preeclampsia (PE) is a disease in pregnancy involving interplay of multiple genetic, immunologic and environmental factors. The primary pathology of PE is related to abnormal placentation. Uterine artery doppler in the first trimester is a promising screening test for prediction of PE. Objective: To study the role of first trimester uterine artery doppler in prediction of preeclampsia. Methods: A prospective study was carried out to evaluate the role of uterine artery doppler in the 11- 14 week scan for prediction of preeclampsia and associated IUGR. A total number of 200 women who met our selection criteria were included in the study. Uterine artery doppler was done as part of the 11-14 weeks scan and mean uterine artery PI was calculated. Results: Among the women in the study, PE was detected in 21 women with incidence of 11 %. The sensitivity, specificity, positive predictive value and negative predictive values of mean uterine artery PI for development of PI were 76%, 86%, 39% and 96% respectively. Conclusions: Early identification of pregnancies at high-risk of early onset PE and undertaking the necessary measures to improve placentation can reduce the burden of the disease by using prophylactic aspirin. Effective screening for early onset PE can be achieved in the first-trimester of pregnancy with maternal history, uterine artery doppler and biochemical markers. Biochemical screening for preeclampsia needs to become cheaper and easily accessible for better prediction of PE in first trimester.

Submental Lipoma-Clinical Report of the Case and Review of the Literature.

Lipomas is the commonest tumour of subcutaneous tissue. It may occur anywhere in the body, but are very infrequent in the head and neck. Clinically they confuse with other soft tissue masses, especially if the present in the head and neck region. Malignancy has to be ruled out if the large neck swelling with increased rapid recent growth. . Improved diagnostic imaging technology (such as CT or MRI) has been very beneficial for the knowledge of extension and surgical plan of the tumour mass.The best treatment modality so far has been surgical excision. In this present study, a 45-year-old woman who presented with a enlarged submental mass which was present since 2 months but has started growing rapidly since 15 days is described. Surgical excision under bilateral cervical block was performed. A 7cm ×4cm mass was successfully removed. The surgery produced no functional impairment and good cosmetic results. Review of literature is also included.