Multiple intracranial aneurysms: incidence and management outcome in King Chulalongkorn Memorial Hospital.

We retrospectively reviewed the 380 patients on whom surgery was performed for intracranial aneurysms between January 1987 and December 1997. The incidence of multiple intracranial aneurysms (MIA) in our hospital was 8.7 per cent (33/380 cases). The management outcome of 33 patients with MIA was assessed 6 months after SAH. The outcome was poorer for patients with MIA than for those with a single intracranialaneurysm (SIA). The mortality and morbidity in all grades were 24.2 per cent in patients with MIA and 16.7 per cent and 19.6 per cent respectively in those with SIA. Delayed neurological deficit and treatment outcome of poor grade patients had significant contribution to outcome in patients with MIA, more than in patients with SIA.

Outcome in treatment of intracranial aneurysm 10 years retrospective study at King Chulalongkorn Memorial Hospital.

The authors retrospectively reviewed 477 patients who were diagnosed with intracranial aneurysm and treated between 1987 and 1997 to evaluate the outcome of treatment. On admission, the patients were graded according to the scale of Hunt and Hess: 96 patients (20.1%) were classified in Grade I, 161 (33.8%) in Grade II, 162 (34.0%) in Grade III, 46 (9.6%) in Grade IV, and 12 (2.5%) in Grade V. At follow-up examination 6 months after SAH, 280 patients (58.7%) were classified as having made a good recovery, 80 patients (16.8%) suffered some morbidity, and 117 patients (24.5%) had died. Surgery was performed in 380 (79.7%) of the patients. Of 124 patients who had surgery within 72 hours, 79 (63.7%) patients made a good recovery. It is concluded that, among patients with all clinical grades, almost six of 10 intracranial aneurysm victims can be saved and can recover to a normal life.

Atypical granular cell tumor of the neurohypophysis: a case report with review of the literature.

A 76-year-old man had an atypical granular cell tumor of the neurohypophysis which showed pleomorphic nuclei, mitotic figures, and spindle-shaped cells, extremely rare findings to be encountered. Review of 45 patients with neurohypophyseal granular cell tumor revealed a ratio of 1:2 between male and female with the peak occurrence (31%) in the fifth decade, and with the mean age of 50 years. There were no patients below 20 years of age. The common clinical presentations included visual disturbances and endocrinopathies relating to sex hormones. Surgical removal was the treatment of choice. If it is possible, total extirpation should be attempted. Because of uncertain cellular origin, the lesion should be descriptively diagnosed as granular cell tumor although multiple terms have been proposed.