Prevalence and Predictors of Depression among Postpartum Mothers in the Limbe Health District, Cameroon: A Cross-Sectional Study.

Depression is a debilitating mood and mental disorder affecting approximately 13% of postpartum mothers worldwide with a prevalence of 25%-60% in low and middle income countries. The prevalence is yet to be published in Cameroon. Aim: This study was carried out to determine the prevalence, severity and risk factors of depression among postpartum mothers in Limbe Health District (LHD), Cameroon. Study Design: It was a cross-sectional, analytic community-based survey. A non- probability convenient sampling method was used to recruit four hundred participants in eight communities in the LHD. Postpartum mothers with infants aged 1-12 months constituted the study population. Data collected using the Patient Health Questionnaire-9 (PHQ-9) and a structured questionnaire was analyzed using Epi-Info version 3.5.4. A p-value of less than 0.05 was considered statistically significant for variables. Results: The prevalence of depression among participants was 61.8% based on PHQ-9 depression scale. The severity of depression varied from mild 54.7%, moderate 43.3% to severe2.0%. Socio-demographic factors associated with depression were: unemployment [OR=2.02;95% CI:(1.35-3.86), p=0.002], unsatisfactory support or assistance for care of baby [OR = 4.89; 95% CI: 2.25-10.612), p = < 0.001], marital conflict [OR = 0.44; 95%CI: (0.23-0.82), p = 0.009] and serious financial problems [OR = 0.31; 95% CI: (0.18-0.54), p =0.002]. Unplanned pregnancy was the only obstetric factor associated with depression [OR=2.02; 95% CI: (1.24-3.29), p= 0.004]. Conclusion: The prevalence of depression among postpartum mothers in the LHD was high. Unemployment, unsatisfactory assistance for child care, marital conflicts, financial difficulties and unplanned pregnancy were risk factors for postpartum depression.

Seroprevalence of Toxoplasma Gondii Infection among Pregnant Women in Cameroon

Toxoplasmosis is caused by an intracellular protozoan; Toxoplasma gondii; which has a wide geographical distribution. The congenital form results in a gestational form that can present a temporary parasiteamia that will infect the fetus. For this reason early diagnosis in pregnancy is highly desirable; allowing prompt intervention in cases of infection. The aim of this study was to determine the seroprevalence of Toxoplasma gondii antibodies among pregnant women attending the Douala General Hospital. The study was carried out between March and July 2009; whereby 110 pregnant women were tested for IgG and IgM antibodies and information about eating habits and hygienic conditions was collected using a questionnaire. These women's ages ranged from 20-44 years old with an average of 29.9 years; the overall IgG and IgM seroprevalence was 70and 2.73respectively. Seroprevalence was significantly high amongst women who ate raw vegetables (76.39; P0.05) and there was a significant trend towards a higher seroprevalence in women who did not have a good source of water (75.58; P0.05). This research showed that consumption raw vegetables and poor quality drinking water are two risk factors associated with Toxoplasma gondii infection amongst pregnant women attending the Douala General Hospital in Cameroon

Genital Mycoplasmas in Women Attending the Yaounde University Teaching Hospital in Cameroon

Genital mycoplasmas are implicated in pelvic inflammatory diseases; puerperal infection; septic abortions; low birth weight; nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility in women. There is paucity of data on colonisation of genital mycoplasma in women and their drug sensitivity patterns. The aim of our study was to determine the prevalence of genital mycoplasmas (Ureaplasma urealiticum and Mycoplasma hominis) infection and their drug sensitivity patterns in women. A mycofast kit was used for biochemical determination of mycoplasma infection in 100 randomly selected female patients aged 19-57 years; attending the University of Yaounde Teaching Hospital (UYTH) from March to June 2010. Informed consent was sought and gained before samples were collected. Genital mycoplasmas were found in 65 patients (65) [95CI=55.7-74.3] and distributed as 41 (41) [95CI=31.4-50.6] for U. urealiticum and 4 (4) [95CI=0.20-7.8] for M. hominis while there was co-infection in 20 women (20) [95CI=12.16-27.84]. In our study; 57 (57) [95CI=47.3- 67] had other organisms; which included C. albicans (19 [19]); G. vaginalis (35 [35]) and T. vaginalis (3 [3]). Among the 65 women with genital mycoplasma; the highest co-infection was with G. vaginalis (33.8). Pristinamycine was the most effective antibiotic (92) and sulfamethoxazole the most resistant (8) antibiotic to genital mycoplasmas. We concluded that genital mycoplasma is a problem in Cameroon and infected women should be treated together with their partners

Social Stigma as an Epidemiological Determinant for Leprosy Elimination in Cameroon

Leprosy has been eliminated as a public health problem in most countries of the world according to the WHO; but the social stigma to the disease is still very high. The present study was performed to investigate the role of social stigma as a determinant for leprosy elimination in a leprosy endemic region of Cameroon. Focus group discussions; in-depth interviews and structured questionnaires were used to investigate leprosy social stigma among lepers; their contacts and a control group consisting of patients attending a health facility for reasons other than leprosy. Informed consent was sought and gained prior to starting the study. Focus group discussions and in-depth interviews identified three types of stigma: lack of self-esteem; tribal stigma and complete rejection by society. From the 480 structured questionnaires administered; there were overall positive attitudes to lepers among the study population and within the divisions (P=0.0). The proportion of participants that felt sympathetic with deformed lepers was 78.1[95confidence interval (CI): 74.4-81.8] from a total of 480. Three hundred and ninety nine (83.1) respondents indicated that they could share a meal or drink at the same table with a deformed leper (95CI: 79.7-86.5). Four hundred and three (83.9) participants indicated that they could have a handshake and embrace a deformed leper (95CI: 80.7-87.3). A total of 85.2(95.0CI: 81.9-88.4) participants affirmed that they could move with a deformed leper to the market or church. A high proportion of 71.5(95.0CI: 67.5-75.5) participants stated that they could offer a job to a deformed leper. The results indicate that Menchum division had the lowest mean score of 3.3 on positive attitudes to leprosy compared with Mezam (4.1) and Boyo (4.8) divisions. The high proportion of positive attitudes among the participants and in different divisions is a positive indicator that the elimination of leprosy social stigma is progressing in the right direction. Quantification of stigma to assess the elimination struggle is a new research area in public health