Cerebrospinal Fluid Polymerase Chain Reaction in the Diagnosis of Neonatal Bacterial Meningitis: A Single-Center Experience From Vietnam

Objective: To compare the performance of cerebrospinal fluid (CSF) polymerase chain reaction (PCR) with bacterial culture for the diagnosis of neonatal bacterial meningitis (NBM). Method: The CSF analysis of neonate with confirmed bacterial meningitis was performed with PCR and bacterial culture, and results were compared. Result: Among 24 neonates, the pathogens Identified included E. coli K1, GBS, Streptococcus pneumoniae and Listeria. PCR identified 20 (83.3%) pathogens, and culture 4 (16.7%) pathogens. Prior antibiotics were administered to 20 (83.3%) neonates in whom PCR identified 17 (85%) and culture 3 (15%) pathogens. Conclusion: CSF PCR had a higher yield of pathogens than CSF culture in confirmed neonatal bacterial meningitis with a high rate of prior antibiotic therapy.

Studying skin temperature feature at 12 couples of Yuan point on patients with gastric - duodenal ulcer

A random study on skin temperature change at 12 couples of Yuan point was carried out on 120 subjects. These subjects were divided into two groups: 60 subjects with duodenal ulcer and 60 healthy subjects served as control. Results: There were difference in skin temperature of bilateral Thai xung point in both male and female with gastric-duodenal ulcer (P<0.05-0.01). Temperature of 12 couples of Yuan point in this group was higher than those in control group (P<0.05-0.001)

Study on serum CRP level of patient with infection allergic bronchial asthma

In the year 1999 at Bach Mai Hospital, serum CRP level was quantified on 21 patients with allergic bronchial asthma without bacterial infection and 38 associated with bacterial infections.In patients of infected allergic bronchial asthma the positive rate of serum CRP was 115,2+/- 6,03 in average, higher than in non infected ones. After treatment, CRP level reduced with statistical significant. In 90,48% of cases of simple allergic bronchial asthma, white blood cell count was normal, while in 92,12% of infected cases, white blood cell count enhanced. There was a positively proportional relation between diverse indices determining inflammative status in the group of patients with infected bronchial asthma

The change of lipoprotein in SLE patient with nephrotic syndrome

In 1999-2000 year period at Bach Mai Hospital, on 26 patients sufferring from systemic lupus erythematosus (SLE) with nephrotic syndrome . SLE developed with higher incidence in women than in men (23 versus 3). Proteine and albumine blood level reduced significantly in comparing with control. Through urine, a quantity of proteine of 4,2g/24 hours lost . Blood lipid of all lipid components enhanced significantly in comparing to control. HDL-C level reduced a little, only in severious patients.There was an inverse proportional relationship between CT,LDL, with HDL; between HDL and CT with albumine contents in plasma

The primary evaluating pulmonary ventilation disorder in asthma patients throught maximum expire volume/second (VEMS) and average flow of expire stage in 25% to 75% of alive capacity

Study on 33 asthma patients and identifying maximum expiring volume per second and medium flow between expiring stage of living volume from 25% to 75% in asthma patients without severe stuffy treated at Bach Mai hospital in 2000. The results: there was no difference of sex in asthma. 24% of patients with childhood asthma; 0.6% of them with asthma over 20 years and 30% of them with asthma from 10 to 20 years. After treatment, medium expiring gaz flow at the middle of expiring stage at 25% to 75% of living volume decreased down 50.8% compared with theory value. 48% of patient with mixture ventilation disorder. 40% of patients with obstructed ventilation disorder, 24% of patients with pheriperal obstructed ventilation disorder

Walking trial for 6 minutes in the indication of long-term oxyde treatment in chronic obstructive pulmonary disease (COPD) patients

Objective: To evaluate the decrease of pulmonary function in patients with respiratory distress in order to help physicians give appropriate indication of oxygenotherapy at home with appropriate doses. Subject: 37 patients and 20 healthy people in control group. Results: There isn't any change in heart rate, FEV1, walking distance, and SaO2 after walk test in healthy people. Elevating in radial artery pulse (+50 in male, +55 in female) represents increasing the need of oxygen during exercise. SaO2 decreases significantly. PaCO2 reduces. Patients can't walk as long as the healthy. Evaluting SaO2 decrease after walk test can help physicians give appropriate indication of oxygenotherapy at home with appropriate doses

A study in the cutaneous conductivity at 12 couples of Yuan points in adults

120 healthy subjects were selected and divided into two groups to study the cutaneous conductivity at 12 couples of Yuan point, group 1 including 60 subjects aged between 21 to 25 (30 males, 30 females), group 2 including 60 subjects aged between 50 to 67 (30 males, 30 females). The results: there was no difference in cutaneous conductivity at 12 couple of Yuan point of the lest and right body in both groups of ages and sexes. In female, cutaneous conductivity at 12 couple of Yuan point were diferent depending on menstrual cycle, considerably lower in the latter haft of the cycle compared to the first half of the cycle. In the same age group, cutaneous conductivity at 12 couple of Yuan point in male was lower than that in female. In the same gender group, cutaneous conductivity at 12 couple of Yuan point of the group 1 was lower that of the group 2

To investigate glomerular filtration in systemic lupus erythematosus patients with renal lesions

Study on 95 systemic lupus erythematosus patients with renal injury treated at Allergy and Immunology Department of Hopital Bach Mai during 2001-2003. The result: renal injury, joint injury, butterfly rash have high rate. Sign of anaemia occur at 92,3% among 78 patients with renal injury. Protein in the urine occur at 100% cases. More 70% of cases occur oedema, less urine and more 20% of cases occur blood in the urine and hypertension. Mean filter level of glomerular of group with renal injury is lower significantly than normal values. Between filter level of glomerular and concentration of ure, creatinin in blood have reverse correlation. More grave renal failure and more decreasing filter level of glomerular are more increasing concentration ure, creatinin and kali in blood

To evaluate hepato-cellular lesions status in drug allergic patient treated in Clinical Immuno-Allergy Department, Bach Mai hospital 2000-2003

The clinical and laboratory characteristics of 139 drug-allergy patients with hepatic cell failure at Allergy and Immunology Department of Hospital Bach Mai from 1999-2003. The result: clinical manifestation of hepatic injury due to drug are very diversified including jaundice, yellow-eyed, ascites, conscious disorder, haemorrhage of skin and mucous, dyspepsia. The laboratory result showed that patients were reduced synthetic process of albumin and protid of liver, coagulation defects due to reducing rate of prothrombin, increasing significantly enzyms of liver. The reason of hepatic cell failure include: traditional drug, psychiatry drug and Rifampicin. Antibiotic drug and epilepsy drug have the same rate

Study on risky factors, allergy history characterictis and treatment effects in asthma patients in Clinical Immunolgy-Allergy Department of Bach Mai hospital, 2000

Study epidemiological features, history of allergy and risk factors of asthma patients treated at Bach Mai Hospital, to evaluate the improvement of clinical symptoms and pulmonary ventilation after treatment. Subjects: 75 patients treated at Bach Mai Hospital from November 2003 to March 2004. Method: retrospective study. Results: Rate of asthma is the highest in group of 20-49 years old. 2 risk factors weather change and exercise exacerbate asthma course. More than 50% patients had history of smoking. There is high rate of patients with history of allergic rhinosinusitis, rash, drug allergy among asthma patient group. 88% patients were treated successfully

Drug allergy status of patients treated in Clinical Immunology Allergy Department of Bach Mai Hospital

Researching on 168 drug allergy medical records at Bach Mai Hospital in 1999 showed that: themselves history was 18.5% and family history was 25%. Drug allergy can occur from many ways: oral, injection and contraction. All drugs aslo make allergy, among them antibiotic and epilepsy drug is higher than other drug. Wound form in clinical was multiform as hives, Quincke beriberi, Stevens-Johnson, Lyell syndrome, red skin, and anapphylactic shock. Allergy rate of Beta-lactam antibiotic is the highest. Using drug without indication make allergy reaction with high rate

To evaluate gaz diffusion capacity of pulmonary by using monoxyde carbone

The study carried on 62 patients with pathology symbol as slacken alveolus , multi-erythrocyte, sclerosis skin and anaemic who were being tested respiratory function at Cochin Paris Hospital from 2001 to 2002. Patients were measured diffusibility CO (DLCO) of pulmonary by respiratory cycle. The result showed that DLCO reduced 62% in slacken alveolus group and 70% in sclerosis skin group in comparison with theoretical valid. Adjustment DLCO according to standard Hb valid 14.6g/dl changed DLCO valid in multi-erythrocyte and anaemic group. The adjust process helped to eliminate really disffuse disorder of pulmonary. DLCO in organ transplant patients were average after adjustment according to Hb and alveolus air volume

The changes of blood gaz after Terbutalin inhalation treatment in asthma patients

Study on 26 degree 2 and 3 asthma patients, treated terbutalin inhalation at Cochin Hospital, Paris from November 2001 to August 2002. The results showed that: blood oxygen deficient status in asthma episode (PaO2: 73mmHg±2.6) account for 54%. Arteries oxygen saturated decreasing status before terbutalin inhalation account for 80%. The blood gaz improvement after beta 2 stimulative drug inhalation expressed parameters: increasing arterial blood oxygen pressure, decreasing PaCO2 pressures, increasing arterial blood oxygen saturation. Terbutalin is a strongly bronchial stretch drug, gaining treatment results in several minutes, improving ventilation thoughout the changes of blood gaz

Preliminary results of the evaluation of respiratory function in asthmatic children

Studying 56 asthma patients, results showed that prevalence of asthma in stage 1 in 3-to-7-years old children was 42%. 12,5% of asthma children experienced chronic cough. 80.5% asthma children had medical history of allergy. House dust mite is a leading cause of asthma (51% patients had positive Prick test). In group 3-7 years old, 37.73% patients experienced obstructive syndrome, among them bronchial obstruction 3.5%, peripheral obstruction 28.79%, total obstruction 5.36%. 57.1% asthma children had improvement of pulmonary ventilation after using bronchodilators. 12.5% patients had increased resistance of airway that was found by breathing interruption method without cooperation of patients

Testosterone like Yang tonic effect of Poliarchis dives (CT1)

The tonic effect of Poliarchis dives (CT1) was studied on the change of weight of the spermatic bag in male mice. Results showed that this preparation enhanced the weight of spermatic bag by 183,33%. Testosterone-like spermatogenesis activity of the preparation was suggested

Metacholin test on early diagnostic of asthma

The test is helpful in early diagnosis of bronchi asthma crisis because of its specificity and high sensitivity with a simple equipment of FDC 88 Medifrom.

Study some allergic reactions with betalactamine in children

Study on 47 children patients have personal history and family history of allergy, age from 4 months to 17 years old in Cochin Paris in 2001. 21.2% of suspicion about having allergic reactions with betalactamine test . The value of diagnosis of test betalactamin is good. There isn’t any positive with RAST reaction. Through history of allergy and test to define the risk factors of high allergy as find out private allergy, acute characteristic level of allergy reaction

Effects of Macrotermes anadelei and Polyrachis dives on process of learning and memorization

The water extracts of Macrotermes anadelei and Polyrachis dives were shown to improve the memorization power of rats at the dose of 10 mg/kg body weight. After the 21-days training for one trial learning avoidance test, the time the rats remained in the bright chamber was reduced to 47.2% for those received M. anadelei, and 43.6% for P. dives, not significantly lower than Ginkgo biloba (50.6%). In Morris Water Maze, both those extracts were also proved to boost the process of learning and memorization in mice.