Is there an association between type 1 diabetes in children and Gallbladder stones formation?

A number of studies in adults have evaluated the prevalence of gallstones in the diabetic population and showed a significant association with type 1 diabetes [T1D] and type 2 diabetes. The pediatric literature is limited to a single small case series. We conducted a cross-sectional study to evaluate for the presence of association between T1D in children and gallstones formation. Children diagnosed with T1D in a diabetic clinic have been examined for existence of gall bladder stone formation from November 2008 through November 2009. All have been subjected to the following: History, physical examination, blood tests [liver function tests, lipid profile, glycosylated hemoglobin [HbA1C]], and an ultrasound [US] of the gall bladder. One hundred and five children with T1D have been enrolled consecutively over a 1-year period: age ranged between 8 months and 15.5 years, 62 patients were females. The mean age at diagnosis was 6.3 +/- 2.9 years [range 0.85-11 years], mean duration of T1D was 2.2 +/- 2.1 years [range 0.2-8 years], mean body mass index was 16.5 +/- 3.4, mean HbA1c was 10.7 + - 2.4%, and 61.3% of patients had a HbA1c level >10%. The mean serum cholesterol was 4.16 +/- 0.75 mmol/L [normal 3.65-5.15 mmol/L] and mean serum triglyceride 1.02 +/- 1.3 mmol/L [normal 0-1.7 mmol/L]. Two patients had hyperlipidemia. US of the gallbladder did not show any case of gallstones or sludge formation. Data from our study do not show any association between T1D in children and gallstones formation, with diabetes duration of less than 8 years. The relatively short duration of diabetes and possibility that our study was underpowered might have been reasons for the absence of any association

Electromagnetic Energy Radiated from Mobile Phone Alters Electrocardiographic Records of Patients with Ischemic Heart Disease

Electromagnetic energy radiated from mobile phones did not show significant effect on the blood pressure; heart rate; and electrocardiographic (ECG) parameters in animals and humans. Aim: This study aimed to investigate the effect of radiofrequency of mobile phone on the electrocardiographic parameters in patients with history of ischemic heart disease; taking into consideration the gender factor . Subjects and Methods: A total number of 356 participants (129 males and 227 females) were admitted in this study. They were grouped into: subjects without cardiac diseases (Group I); patients with ischemic heart disease (Group II); and patients with history of cardiac diseases not related to myocardial ischemia (Group III). Electrocardiogram was obtained from each patient when the mobile phone was placed at the belt level and over precordium in turn-off mode (baseline) and turn-on mode for 40 sec ringing. The records of ECG were electronically analyzed. Results: Prolongation of QTc interval was significantly observed in male gender of Groups I and III (P 0.001). Male patients of Group II showed significant QTc interval prolongation (P

Unusual presentation of splenic abscess

Splenic abscess is known to occur as a very rare cause of intraabdominal sepsis. Only ten cases were reported in the USA until 1942, and no more than one case is now being diagnosed annually in any large centre

Efeito de uma dieta rica em fibras sobre o transito intestinal. / Effect of a rich fiber diet on the intestinal transit

Estudos epidemiologicos tem demonstrado uma diminuicao do tempo de transito intestinal nas populacoes que ingerem alimentacao rica em fibras. Nos paises mais desenvolvidos a industrializacao tem sido apontada como responsavel pela reducao do conteudo de fibras das dietas. A menor ingesta de fibra tambem tem sido correlacionada com diversas doencas como: diverticulose, hemorroidas, varizes de membros inferiores diabetes, obesidade, aterosclerose. O presente trabalho foi realizado com a finalidade de demonstrar o efeito das fibras sobre o transito intestinal. O estudo foi realizado em 9 pacientes internados na Unidade Metabolica da Disciplina de Nutrologia, Departamento de Clinica Medica, Faculdade de Medicina de Ribeirao Preto. Os pacientes receberam uma dieta de alimentos regionais e normalmente usados na nossa alimentacao.As fibras destes alimentos foram calculados como fibra bruta. Foi medido o tempo de transito em 2 periodos separados e cada periodo constava no minimo de 7 dias. Os resultados do transito no periodo com conteudo normal de fibras (4,6 +/- 0,4 gramas) foi de 37,0 +/- 9,6 horas e no periodo com dieta rica em fibras (11,5 +/- 2,1) foi de 23,0 +/- 11,3 horas.O tempo de desaparecimento dos corantes nas fezes nao mostrou associacao significativa em relacao a quantidade de fibra ingerida pelos pacientes