Effect of successive infestation of adult ticks of hyalomma annatolicum on chinchilla rabbits

The effect of successive infestation of Hyalomma annatolicum annatolicum adult ticks was studied on Chinchilla Rabbits. The difference in engorgement blood ingestion in the first application in the experimental animals was insignificant but on second application on the experimental animals it was significant as compared to the control animals. In the third and fourth applications the experimental animals the difference in the engorgement was more reduced as compared to the control animals [P <0.05]. Therefore it is concluded that engorgement was reduced due to the development of immunity of the skin by subsequent infestation of adult ticks on Chinchilla Rabbits

Cellular response stimulated by tick bit in laboratory animals

Neutrophils were found significant when 500 larvae and 50 adults of Rhipicephalus appendiculatus were infested on the rabbit, when 10 nymphs were applied to guineapigs the lymphocytes were significant at 144 hours in guinea pigs. It is concluded that intense infiltration of neutrophils is similar to Arthus and Schwartzman reaction in rabbits, lymphocyte infiltration in guineapigs in similar to that associated with delayed allergy in skin