RESUMO
The aim of this study was to assess the prevalence of insulin resistance [IR] in healthy young Omanis and relate this with their body mass index [BMI] and family history [FH] of diabetes mellitus [DM]. This study was conducted between May 2009 and February 2010 at Sultan Qaboos University, Muscat, Oman. A detailed questionnaire was completed by 50 male and 50 female medical students between 20-25 years old. Fasting blood samples were obtained for serum glucose and insulin measurements. IR was calculated using the homeostasis model assessment-estimated insulin resistance [HOMA-IR] formula [fasting insulin x fasting glucose/22.5] and a value above 2.5 was considered elevated. The results were analysed using the Statistical Package for the Social Sciences [SPSS]. Participants were classified into the following BMI categories: 59% were normal [18.5-24.9 kg/m[2]], 26% were overweight or obese [>24.9 kg/m[2]] and 15% were underweight [<18.5 kg/m[2]]. A FH of DM was present in 74%. The HOMA-IR index was elevated in 16% and was directly correlated to the BMI [P = 0.003]. There was no correlation between IR and a positive FH of DM. There is a high prevalence of IR [16%] and obesity [26%] in healthy young Omani medical students. Counselling is recommended for all overweight and obese individuals in an attempt to prevent or delay the onset of DM in the future