Pelvic organ prolapse in peri urban area of Karachi

To study prevalence, presentation and management of utero vaginal prolapse in Lyari [a periurban area of Karachi] A cross sectional study The study was conducted in Gyn/Obs department of Lyari General Hospital from 1st July 2005 to 30th June 2006. During this period 40 gynae admissions were cases of utero vaginal prolapse. After detailed history, examination and initial work up planned surgery was performed. All patients were followed in OPD after 6 weeks of operation During 1 year study period out of 376 gynae admissions 40 were cases of uterovaginal prolapse. So prevalence of utero vaginal prolapse in Lyari is 9.4. All were OPD admissions except 1 with incarcerated prolapse admitted through emergency. Around 50% were >50 years of age and 75% were grandmultipara. Main presenting complaint [100%] was vaginal protrusion. vaginal hysterectomy with anterior and posterior repair was done in 62.6%. Median length of stay was 5-7 days. Very few cases had intraoperative and postoperative complications. None had mortality

Iron status in pregnancy complicated with preeclampsia

The present study was undertaken to evaluate the iron-status in preeclampsia and a possible contributory role of iron in the etiology of preeclampsia. The study subjects were classified into two groups, normal healthy pregnant women as a control and preeclamptic group. The blood was used for estimation of hemoglobin and haematocrit while serum was used to assess the serum iron, total iron binding capacity [TIBC] and serum ferritin. Significantly increased levels of iron, serum ferritin and transferrin saturation were found in preeclamptic as compared to control group. The total iron binding capacity [TIBC] and unsaturated iron binding capacity [UIBC] were significantly decreased in preeclamptic group as compared to the control group. It was concluded from this study that increased level of serum iron may be implicated in oxidative stress in preeclampsia but no positive correlation was found between serum iron, serum ferritin, total iron binding capacity and elevated blood pressure in preeclamptic group