RESUMO
Tuberculosis is an important opportunistic infection in HIV/AIDS. Benue state is the highest HIV endemic state in Nigeria and investigation of tuberculosis cases and Mycobacterial resistance patterns are needed. A retrospective study with a review of reports of Mycobacterium tuberculosis and the rifampicin resistance was detected by the Cepheid GeneXpert MTB/RIF system was carried out from July, 2012 to September, 2013 in Federal Medical Centre, Makurdi and Nigeria Airforce Hospital, Makurdi. Pulmonary tuberculosis was detected in 21.5% (n=303/1407) of the total sample. Rifampicin resistance of 13.5% (31/230) and 15.1% (11/73) of the pulmonary tuberculosis positive cases was detected in Federal Medical Centre and Nigeria Airforce Base Hospital respectively, with an average prevalence of 13.9% (42/303). Re-treatment cases comprised 81% (34/42) whereas new cases constituted 19% (8/42) of all Rifampicin resistant Mycobacterium tuberculosis positive cases (X 2 = 6.51; p<0.05). Mean age was 30 years and there was no significant statistical difference in gender. Rifampicin resistant Mycobacterium tuberculosis is prevalent in Benue state, Nigeria especially, in the young adults. Therefore, laboratory facilities for rapid diagnosis of the drug resistant M. tuberculosis should be scaled up across the country. This remains an important step to achieve maximal impact in managing drug resistance in Nigeria.
RESUMO
Objectives: The study was to determine the distribution of male urethral discharge among the patients seen in primary health care centres of Jos North Local Government Area. Methods: Male patients with urethral discharge were recruited during their clinic days; from September 2004 to May 2006. A structured questionnaire was administered to the patients who gave their consent. Pre-treatment and post-treatment urethral samples were collected and processed according to standard laboratory procedures. Results: One hundred and seventy-six out of 200 patients completed the study. The age range and mean age of the patients were 11-60 years and 30.7 years respectively. The age decade 21-30 years constituted 100 (56.8) of 176 patients; commercial motorcyclists contributed 80 (45); the single marital status recorded 106 (60.2) while primary and secondary education status had 141 (80). Conclusion: Commercial motorcyclists recorded the highest risk of male urethral discharge; and the peak was among young adults of age decade 21-30 years; especially among the single and less educated