Effect of Pneumoperitoneum on Oxidative Stress and Inflammation via the Arginase Pathway in Rats

PURPOSE: Oxidative stress during CO2 pneumoperitoneum is reported to be associated with decreased bioactivity of nitric oxide (NO). However, the changes in endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS), and arginase during CO2 pneumoperitoneum have not been elucidated. MATERIALS AND METHODS: Thirty male Sprague-Dawley rats were randomized into three groups. After anesthesia induction, the abdominal cavities of the rats of groups intra-abdominal pressure (IAP)-10 and IAP-20 were insufflated with CO2 at pressures of 10 mm Hg and 20 mm Hg, respectively, for 2 hours. The rats of group IAP-0 were not insufflated. After deflation, plasma NO was measured, while protein expression levels and activity of eNOS, iNOS, arginase (Arg) I, and Arg II were analyzed with aorta and lung tissue samples. RESULTS: Plasma nitrite concentration and eNOS expression were significantly suppressed in groups IAP-10 and IAP-20 compared to IAP-0. While expression of iNOS and Arg I were comparable between the three groups, Arg II expression was significantly greater in group IAP-20 than in group IAP-0. Activity of eNOS was significantly lower in groups IAP-10 and IAP-20 than in group IAP-0, while iNOS activity was significantly greater in group IAP-20 than in groups IAP-0 and IAP-10. Arginase activity was significantly greater in group IAP-20 than in groups IAP-0 and IAP-10. CONCLUSION: The activity of eNOS decreases during CO2 pneumoperitoneum, while iNOS activity is significantly increased, a change that contributes to increased oxidative stress and inflammation. Moreover, arginase expression and activity is increased during CO2 pneumoperitoneum, which seems to act inversely to the NO system.

The Structural Equation Model on Resilience of Breast Cancer Patients Receiving Chemotherapy

PURPOSE: The purpose of this study was to construct and test a structural equation model on resilience of breast cancer patients receiving chemotherapy. METHODS: Participants were 204 patients with breast cancer who received chemotherapy treatment. They participated in a structured interview, which included social support, depression, symptom experience, self-efficacy, hope, resilience, and infection prevention behaviors. Data were analyzed using SPSS/WIN 20.0 and AMOS 18.0. RESULTS: Lower depression (γ=-.33, p=.020) and symptom experience (γ=-.31, p=.012) and higher self-efficacy (γ=.32, p=.005) and hope (γ=.48, p=.016) were influenced by higher social support. Greater resilience was influenced by lower symptom experience (β=-.18, p=.016), higher self-efficacy (β=.49, p=.023), and higher hope (β=.46, p=.012), and these predictors explained 66.7% of variance in resilience. Greater resilience (β=.54, p=.009) made an impact on greater infection prevention behaviors. Resilience mediated the relations of symptom experience (β=-.10 p=.013), self-efficacy (β=.27, p=.006) and hope (β=.25, p=.009) with infection prevention behaviors. These predictors explained 24.9% of variance in infection prevention behaviors. CONCLUSION: The findings of the study suggest that breast cancer patientsw ith greater resilience who are receiving chemotherapy participate in increased infection prevention behaviors. Further research should be conducted to seek intervention strategies that improve breast cancer patients' resilience.

Characteristics and Factors Associated with Problem Drinking in Male Workers

PURPOSE: This study aimed to identify the characteristics and factors related to problem drinking in male workers. METHODS: This study was conducted using a cross-sectional survey and 232 male workers, who completed self-reported questionnaires addressing alcohol consumption, drinking motives, job stress, supervisor/coworker support, and family support. Multivariate analysis was used to uncover factors associated with problem drinking. RESULTS: As compared with normal alcohol users, problem drinkers were more likely to smoke and had greater family support and coping motivations, and fewer confirmatory motives. Problem drinking was found to be related to perceived health status (adjusted odds ratio [OR] = 0.78, 95% confidence interval [CI] [0.64, 0.95]), current smoking (adjusted OR = 2.79, 95% CI [1.26, 6.18]), family support (adjusted OR = 2.04, 95% CI [1.23, 3.39]), confirmatory motivation (adjusted OR = 0.60, 95% CI [0.37, 0.96]), and coping (adjusted OR = 1.79, 95% CI [1.04, 3.07]). CONCLUSIONS: Our findings suggest that any interventions targeting problem drinking among male workers must address smoking cessation, control of stress, and the improvement of drinking subculture in the workplace.

Skin Hydration Status and Skin Surface pH According to the Body Parts of the Aged with Immobilization / 기본간호학회지

PURPOSE: This study was performed to identify skin hydration status and skin surface pH according to the body parts of the aged with immobilization. METHODS: The subjects were 101 aged patients in a hospital and a institution for the elderly in Seoul. Data for skin hydration and skin surface pH were collected using corneo-meter and skin pH-meter. The body parts of measurement were 10 parts; face, forearm, back of the hand, flank, upper abdomen, leg, back of the foot, heel, scapular, and sacrum. The data were analyzed by SPSS/WIN 12.0 program. RESULTS: Skin hydration status were relatively low especially on lower extremity and back of body, and skin surface pH of scapular and sacrum were high. There was significant negative correlation between skin hydration status and skin surface pH on the 6 body parts. CONCLUSION: Skin hydration status and skin surface pH, especially on scapular, sacrum, and lower extremity need to be considered as important control factors for increasing skin health status of the aged with immobilization.

Cognitive Function, Depression, Social Support, and Self-Care in Elderly with Hypertension / 성인간호학회지

PURPOSE: The purpose of this study was to examine the relationship among cognitive function, depression, social support, and self-care in elderly with hypertension. METHODS: The subjects were 132 elderly with hypertension living in Seoul, Korea. Data were collected through face-to-face interviews using the Korean version of Mini-Mental State Examination(MMSE-K), Short form geriatric depression scale, social support questionnaire 6, and hypertension self-care scale. RESULTS: Thirty-four percent of the subjects had questionable dementia and forty-two percent of the subjects were depressed. Means for social support were 2.40 for network size and 4.07 for satisfaction. The mean score of hypertension self-care was 60.34, indicating that the subjects took care of themselves moderately well. Cognitive function was negatively related to depression. Social support network and satisfaction were negatively related to depression. Self-care was negatively related to social support network. CONCLUSION: Programs are needed for elderly with hypertension to improve their cognitive function, depression, and social support. Also further studies are needed to confirm the factors related to self-care in the elderly with hypertension.

The trends of Nursing Research in the Journal of Korean Academy of Adult Nursing / 성인간호학회지

PURPOSE: The purpose of this study was to analyze the published articles in the Journal of Korean Academy of Adult Nursing from 2004 through 2006. METHODS: Two hundreds and ten articles were analyzed focusing on research methodology and key words using descriptive statistics. RESULTS: The proportion of quantitative research was 88.1%, while the proportion of qualitative research was 5.2%. The majority of the qualitative research design was survey(67.1%). Seventy-four percent of the research had verbal consent and 8% had written consent from the participants. Eight percent of the research provided conceptual framework. The prevailing data collection settings were hospitals(50.5%) and community(37.1%). For the data analysis, 95% used parametric analysis methods; descriptive statistics(26.2%), chi-square test(18.3%), t-test(18%) and ANOVA(17.4%). Key words were categorized into four nursing domain: human, health, nursing, and environment. The most frequently used domain was health. CONCLUSION: The number of the published articles in the Journal of Korean Academy of Adult Nursing has been increased and quality has been improved compared with the articles published before the 2000 year. Varied research methodology and data analysis methods were utilized.

Stress, Depression and Health Risk Behaviors in Korean Elders

PURPOSE: The purpose of this study was to investigate stress, depression and health risk behaviors in elderly people. METHODS: The subjects were 238 Korean elders who had visited the convalescent center. The level of stress was measured by the Korean version of BEPSI, which was developed by Bae, Jeung & Yoo (1992) and modified by Yim et al.(1996). CES-D was used to measure the level of depression. For health risk behaviors, we measured cigarette consumption and alcohol drinking during the last one month. RESULTS: Of the subjects, 17.4% were excessive drinkers and 18.9% were currently smokers. The level of stress was between moderate and high, and 62.7% of the subjects were depressed. There were significant differences in stress and depression according to economic status and self-reported health. In addition, depression had positive correlations with stress and QF score. CONCLUSION: Stress and depression management programs for the elderly are needed. These findings indicate that nurses must consider stress and alcohol drinking when they take care of depressed elderly people.

Leisure Activities, Cognitive Function and Depression in Female Elderly / 성인간호학회지

PURPOSE: The purpose of this study was to investigate cognitive function, leisure activities and depression in female elderly, to examine the relationships among those variables and to investigate leisure activities and depression according to cognitive function. METHODS: The subjects were 105 female elderly visiting two senior citizen centers in Seoul, Korea. Data were collected from November to December 2006. The participants were assured of anonymity and confidentiality. All information was collected through face-to-face interviews using questionnaires. RESULTS: 26.0% of the participants were cognitive impaired but not demented and 17.3% were demented. The level of depression was severe and 77.9% of the subjects were depressed. The subjects were not actively engaging in leisure activities. There were significant correlations between cognitive function, leisure activities and depression in female elderly. Demented or CIND subjects were more actively engaging in extra family fulfillment type leisure activities than normal subjects, CONCLUSION: These findings showed the need for a program for female elderly regarding leisure activities. When counseling the elderly, nurses must consider their cognitive function, leisure activities and depression.

Family Support, Alcohol Consumption and Drinking Motives in Patients with Liver Cirrhosis / 성인간호학회지

PURPOSE: The purpose of this study were to investigate the level of family support, alcohol consumption and drinking motives in patients with liver cirrhosis and to examine the relationships among those variables. METHODS: The subjects consisted of 60 patients with liver cirrhosis. Family support scale, Q-F methods and Drinking Motives Questionnaire were used to measure the level of family support, alcohol consumption and drinking motives. RESULTS: The level of family support was 43.62. Prevalence of drinking was 90% and 43.3% were currently heavy drinkers. Alcohol consumption was related to sex and education. There were positive low relationships between the level of enhancement motive, coping motive, social motive, and Q-F Index. CONCLUSION: Alcohol drinking is a serious health problem in patients with liver cirrhosis. It is necessary to have an educational approach for controlling drinking and family support.

Cigarette Smoking, Stage of Smoking Cessation, Nicotine Dependency, and Urine Nicotine Among Smoking Adults with Diabetes / 성인간호학회지

PURPOSE: The purpose of the study was to investigate the level of smoking, process of smoking cessation, and nicotine dependency, and urine nicotine among adults with diabetes which are smokers and to examine the relationship among those variables. METHOD: The subjects consisted of 62 adult men smokers with diabetes mellitus. FTQ and NicCheck 1 were used to measure the level of nicotine dependence. The amount of cigarette smoking was measured by the number of cigarette packs use per week. The stage of smoking cessation was measured by the Prochaska's method. RESULTS: The Subjects smoked cigarettes with a mean of 5.97 packages per week. Seventy-seven percent of the subjects had a nicotine dependency. Fifty-two percent had a high level of nicotine dependency in urine nicotine. Nineteen percent were in the precontemplation stage. The level of cigarette consumption was related to nicotine dependence and urine nicotine. Also, nicotine dependency was related to urine nicotine. CONCLUSION: A tailored smoking cessation program is needed to prevent the chronic complication for diabetes smokers. Self-reported smoking and nicotine dependency seemed to do equally well as NicCheck 1 in assessing nicotine intake.

Cigarette Smoking, Stage of Smoking Cessation, Nicotine Dependency, and Urine Nicotine Among Smoking Adults with Diabetes / 성인간호학회지

PURPOSE: The purpose of the study was to investigate the level of smoking, process of smoking cessation, and nicotine dependency, and urine nicotine among adults with diabetes which are smokers and to examine the relationship among those variables. METHOD: The subjects consisted of 62 adult men smokers with diabetes mellitus. FTQ and NicCheck 1 were used to measure the level of nicotine dependence. The amount of cigarette smoking was measured by the number of cigarette packs use per week. The stage of smoking cessation was measured by the Prochaska's method. RESULTS: The Subjects smoked cigarettes with a mean of 5.97 packages per week. Seventy-seven percent of the subjects had a nicotine dependency. Fifty-two percent had a high level of nicotine dependency in urine nicotine. Nineteen percent were in the precontemplation stage. The level of cigarette consumption was related to nicotine dependence and urine nicotine. Also, nicotine dependency was related to urine nicotine. CONCLUSION: A tailored smoking cessation program is needed to prevent the chronic complication for diabetes smokers. Self-reported smoking and nicotine dependency seemed to do equally well as NicCheck 1 in assessing nicotine intake.

Influencing Factors on HRQOL of Physically Disabled Persons / 간호학회지

PURPOSE: The purpose of this study was to investigate the influencing factors on health-related quality of life of physically disabled persons. METHOD: Data was collected from 96 persons with a physical disability in three cities in Korea from June to September, 2003. Social support and depression were measured by a Social Support Questionnaire 6 (SSQ6) and Center for Epidemiologic Studies Depression questionnaire (CES-D). The Rosenberg Self-esteem Scale was used to measure self-esteem. Health-related quality of life (HRQOL) was measured using Smith Kline Beecham Quality of Life Scale (SBQOL). The SPSS WIN 11.0 version program was used for data analysis. RESULT: There were significant differences of HRQOL according to monthly income and economic status. All subjects had a high level of depression and low self-esteem. CONCLUSION: The findings of this study show that self-esteem and the size of the social support network are significant influencing variables on HRQOL in physically disabled persons. Nursing intervention and counseling programs which improve self-esteem and increase the size of a social support network are needed to promote HRQOL in physically disabled persons.

Descriptive Correlational Study on Personality Type using MBTI and Job Satisfaction / 기본간호학회지

PURPOSE: This study was done to examine the correlations between personality type and job satisfaction of nurses. METHODS: Subjects included three hundred twelve nurses ages from 21 to 55. The Myers-Briggs Type Indicator(MBTI) was administered to determine the personality types of the nurses(n=312). A job satisfaction survey including a demographic and career questionnaire was also used. Data were analyzed using ANOVA. RESULTS: The mean score for job satisfaction was 113.68 out of 205. The result showed that there was no statistically significant correlation between job satisfaction and information gathering functions ; S: Sensing, N: Intuition (t=.667, p=.499), T: Thinking, F: Feeling (t=.822, p=.412). The results, however, indicated that style for gaining energy(I: Introversion, E: Extroversion)(t=2.008, p=.046) and life dealing style(J : Judgement, P : Perception)(t=2.290, p=.023) were significantly correlated with job satisfaction. The extrovert focuses on the outside and get energy through interacting with people and doing things. Judgement type is described as organized, decisive, and orderly. CONCLUSION: Nurses in the extrovert and judgement types were more satisfied with their jobs than those in the introvert and perceptive type. Other results support that educational level, marital status, job characteristics, clinical experiences, motivation for nursing, and night duty were correlated with job satisfaction.

Dependency, Abuse, and Depression by Gender in Widowed Elderly / 간호학회지

PURPOSE: The purpose of this study was to investigate the effects of dependency and abuse on depression according to gender in widowed elderly. METHOD: A convenient sample consisted of 246 widowed elderly who were more than 65 years old in four cities. Data was collected using a structured questionnaire from August to September, 2002. A dependency Scale developed by Ahn (1999) was used to measure the level of dependency. Emotional abuse and physical abuse were measured by 10 items for emotional abuse and 7 items for physical abuse selected out of the Conditions Scale of Elder Abuse. The level of depression was measured by the Geriatric Depression Scale (GDS).The SPSS WIN 11.0 version program was used for data analysis. RESULT: In male widowed elderly, dependency affected depression indirectly through emotional abuse. While in female widowed elderly, dependency affected depression directly and affected emotional abuse indirectly. CONCLUSION: The study showed that dependency was the most explainable variable on depression in widowed female elderly. Therefore, it dependency should be assessed first in nursing intervention to relieve depression of widowed elderly.

Influencing Factors that Affect the Psychological Well-being in Family Caregivers of Stroke Patients / 간호학회지

PURPOSE: The purpose of this study was to investigate the factors that affect the psychological well-being in family caregivers of stroke patients. METHOD: The General Health Perception, short form 36, Health Survey Questionaire was used to measure health perception. The Caregiving Mastery Scale was used to assess the mastery, while the Psychological General Well-Being Index was used to examine the level of well-being. RESULT: Subjective health, caregiving mastery, patient's ADL and caregiving duration influenced on caregiver's psychological well-being. Subjective health had effect on psychological well-being both directly and indirectly. Caregiving duration and patient's ADL had indirect effect on psychological well-being through caregiving mastery. CONCLUSION: It is need to develop a health program for the caregivers of stroke patient's and to provide nursing intervention to improve the caregiver's ability, thereby improving the well-being of the family caregivers.

Alcohol Consumption and Cigarette Smoking in Men with Diabetes Mellitus / 성인간호학회지

PURPOSE: The purpose of the study was to investigate the level of cigarette smoking and alcohol consumption in men with Diabetes Mellitus and to examine the relationships among those variables. METHOD: The subject consisted of 152 adult men with diabetes mellitus. Q-F methods and FTQ was used to measure the level of alcohol consumption and nicotine dependency. The amount of smoking was measured by the number of cigarette packs used per week. RESULTS: Prevalence of drinking was 63.6% and in the current drinkers, 34.4% were heavy drinkers. The prevalence of cigarette smoking was 36.2% with a mean of 6.03 packs per week. Twenty percent of the smokers were dependent on nicotine. Subjects who had complications or other diseases drank alcohol more than who had not. There was a positive relationship between the level of smoking and nicotine dependency. CONCLUSION: Alcohol drinking and cigarette smoking is a serious health problem in men with diabetes. It is necessary to have an educational approach for controlling drinking and smoking in diabetes patients.

Depression in Physically Disabled Persons / 성인간호학회지

PURPOSE: The purpose of this study was to investigate whether subjective health and social support influence depression directly or indirectly through self-control of the physically disabled. METHOD: A five item General Health Short Form (SF-36) Health Survey Questionnaire was used to measure subjective health. Social support and self-control were measured by Social Support Questionnaire 6 and Mastery Scale. The level of depression was measured by CES-D (Center for Epidemiologic Studies Depression). RESULT: The level of depression was high (M=22.23). Seventy percent of the subjects were depressed. Subjective health and satisfaction with social support influenced self-control. Subjective health influenced the level of depression directly and indirectly, but self-control influenced the level of depression only directly. CONCLUSION: Subjective health and satisfaction with social support influenced depression through self-control in physically disabled persons. Therefore, when we manage these subjects' depression, it is seemed that program which lowers the level of depression by assessing and correcting these factors should be prepared.

The Relationships among Loneliness, Social Support,and Family Function in Elderly Korean / 간호학회지

PURPOSE: To examine the relationships among loneliness, social support, and family function in elderly Korean. METHOD: The sample for this study were 290 elderly Korean who were at least 60 years of age. Data were collected by interview using the translated Korean versions of the Revised University of California Los Angels Loneliness Scale(RULS), Family APGAR, and Social Support Questionnaire 6. RESULT: Subjects were moderately lonely and had moderately functional families. Means for social support were 1.42 for network size and 4.09 for satisfaction. Subjects who lived with their spouses had a larger number of network members than who did not live with spouses. However, living with spouses was not associated with social support satisfaction. The level of loneliness was related negatively to the level of social support network, social support satisfaction and family function in this study. Social support satisfaction and Family function were the significant predictor of loneliness. CONCLUSION: The number of social supporter and satisfaction and family function should be considered in nursing intervention to decrease the level of loneliness in older adults. Further studies and efforts will be needed to reduce the level of loneliness in older adults.

The Relationships among Social Support, Stress, and Loneliness in Migrant Yanbian Korean Workers / 성인간호학회지

PURPOSE: The purpose of the study was to examine the relationships among social support (network, composition, and satisfaction), stress, and loneliness in migrant Yanbian Korean workers. METHOD: Data were collected by using Social Support Questionnaire 6, Visual Analogue Scale, and the Revised UCLA Loneliness Scale. RESULT: Results indicate that means for social support were 1.52 for network size and 4.83 for satisfaction. The proportion percentage of network for kin members was 67.37. Subjects felt the moderate level of stress and loneliness. The level of loneliness was negatively related to the level of social support. CONCLUSION: This study showed that there is necessity to reduce stress and loneliness among migrant Yanbian Korean workers. Adequate social support satisfaction is crucial to reduce the level of loneliness in migrant Yanbian Korean workers.

BMI, Weight Control Behavior, and Self-esteem in High School Adolescents / 성인간호학회지

PURPOSE: This descriptive study was designed to investigate Body Mass Index(BMI), weight control behavior, and self-esteem in high school adolescents. METHOD: The convenience sample consisted of 129 high school females and 106 high school males. Data were collected using a self-report questionnaire from November to December, 1999. BMI was calculated by using the subject's self-reported body weight and height to identify objective obesity. Self evaluation about subjective obesity was measured by a single item question. Preferred BMI was calculated by using the subject's self-reported body weight and height which the subjects desired. The Rosenberg's Self-Esteem Scale was utilized to measure the level of self-esteem. RESULTS: Results of the study revealed that high school females perceived themselves as more more obese than their the actual BMI, excessively participated in dieting behavior and exercises, and reported lower self-esteem than that of males. CONCLUSION: Based on this study, health care providers need to educate female adolescents about healthy behavior as well as the normal weight range in BMI.