[Lipoma of the uterus: clinical and ethiopathological approach of 7 cases with immunohistochemical study of histogenesis]

Lipoleiomyoma of the uterus [LLU] is an extremely rare, benign, uterine tumour. This rare disease was unknown for a long time. Their histogenesis remains controversial. To describe the clinical and pathological aspects of uterine lipoleiomyoma and to try to specify, by an immunohistochemical study, its degenerative or tumoral nature. 7 cases of LLU were identified represented by 2 pure Lipoma and 5 Lipoleiomyoma. We performed an immunohistochemical study including anti-vimentin, anti-smooth muscle actin, anti PS-100, anti-desmin, anti-factor VIII and anti-HMB- 45. The results were correlated with the pathogenesis of this lesion. Immunohistochemical analysis showed an expression of PS 100 only in lipocytes whereas leiomyomatous cells express only smooth muscle actin. Our study supports the benign tumoral nature of the fatty uterine lesions. Lipoleiomyomatous cells may originate from the transformation of a totipotent mesenchymal cell and not from a degenerative process

[Microcystic serous pancreatic cystadenoma]

The pancreatic cystic serous neoplasms are divided into two categories: benign serous cystadenoma [SCA] and malignant serous cystadenocarcinoma. Furthermore, based on the macroscopic appearances, SCAs are subdivided into serous microcystic adenomas [SMAs] and serous oligocystic or macrocystic adenomas. Report of a new case of SMA in which we emphasize on the diagnostic difficulties encountered against such tumor despite its relatively radiological easiness compared to the other variants. We report the case of 84 year-old-woman with a microcystic serous cystadenoma of the pancreas which was identified on pathologic examination of the surgical specimen, after unconclusive abdominal ultrasound and computed tomography [CT]-scan. This case describes this rare entity and emphasizes that the diagnosis of such entity is still based on pathological examination after tumor removal

[Parotid basal cell adenoma of membranous type]

Basal cell adenoma [BCA] is a rare benign neoplasm characterized by the basaloid appearance of the tumour cells and the lack of myxochondroid stromal component present in pleomorphic adenoma. We report a case of basal cell adenoma of membranous type, highly suspected of malignancy because of the presence of mediastinal lymph nodes and pulmonary nodules which finally were related to an associated sarcoidosis. Our patient was an 80-year-old woman who presented a swelling of the right parotid two years ago. The clinical examination revealed a solid, indolent and mobile mass. A chest radiography noted mediastinal lymph nodes. The CT-scann confirmed the presence of mediastinal and tracheal lymph nodes with pulmonary nodules. So the diagnosis of metastatic malignant salivary gland tumor was suspected. Finally, the histological examination concluded to a basal cell adenoma of membranous type with sarcoidosis granulomas in the parotid and in the lymph nodes. The BCA is a benign tumor located generally in the parotid gland. When the malignancy is suspected, like in our case, this tumor must be differentiated from the basal cell enocarcinoma using histological criteria

[Signonasal leiomyoma: an exceptional localization]

Most of the sinonasal tumours are of epithelial origin. Leiomyomas are very uncommon in the upper respiratory tract and extremely rare in the nasal cavity and paranasal sinuses. They account for less than 2.5% of the mesenchymal neoplasms of the sinonasal tract and the nasopharynx. Report of a new case which will be added to the 30 cases of primary sinonasal leiomyogenic tumours reported in the litterature. The clinical and pathological characteristics of this tumour will be discussed. We report a case of 48-year-old woman complaining of nasal obstruction corresponding to a polypoid lesion of the sinonasal cavity. The histological examination of the removed mass concluded to a leiomyoma. Leiomyoma in this location has no specific physical or radiological findings. Only the histological examination can definitively made the correct diagnosis

[Solid pseudopapillary tumors of the pancreas: a pediatric case report]

Solid pseudopapillary tumors of the pancreas are extremely rare and mostly seen in young females. It is often diagnosed incidentally or during investigations of gastrointestinal complaints. Report of a pediatric case of this tumor. We report the case of a 15-year old teenager who presented with painful abdominal tumefaction. Imaging findings were a 12 cm solid and cystic mass originating from the tail of the pancreas. A distal pancreatectomy with splenectomy was performed. Pathologic examination concluded to solid pseudopaprillary tumor. Evolution was favorable with no recurrence 18 months after surgery. Histological examination confirms the diagnosis and allows, with the help of immunohistochemical study, to rule out some differential diagnoses such as pancreatoblastoma, acinar tumors and endocrine tumors. Prognosis of solid pseudopapillary tumors of the pancreas is excellent after radical resection and recurrences are rarely seen