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Rev. Soc. Bras. Med. Trop ; 54: e20200087, 2021. tab, graf
Artigo em Inglês | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136920

RESUMO

Abstract INTRODUCTION: In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region. METHODS: The isolates were identified by MALDI-TOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE). RESULTS: Only 10 (55.6%) isolates harbored the gene bla OXA-23. PFGE analysis revealed that these isolates belong to a single clone. CONCLUSIONS: This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced.


Assuntos
Humanos , Infecções por Acinetobacter/epidemiologia , Acinetobacter baumannii/genética , Proteínas de Bactérias/genética , beta-Lactamases/genética , Brasil/epidemiologia , Resistência a Medicamentos , Testes de Sensibilidade Microbiana , Eletroforese em Gel de Campo Pulsado , Epidemiologia Molecular , Hospitais , Antibacterianos/farmacologia
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