A Study Of Perioperative Cardiovascular Events In Non-Cardiac Surgery

Background:Perioperative evaluation is an important step before considering a patient for surgery to deal with cardiovascular risk factors.The aim of the study is to e valuate the risk of cardiovascular events during perioperative period in non-cardiac & non-vascular surgery, even in patients with no previous evidence of cardiac disease.Material And Methods:All patients admitted in Orthopaedic, Surgery, Gynaecology department were evaluated clinically as well as with laboratory and radiological investigation. All patients with age > 40 years were subjected to electrocardiography. All the data was collected & recorded in standard Proforma. Clinical evaluation was done preoperatively & 24 hour post operatively. In patients developing cardiovascular complications, additional evaluation was done on the basis of need. Result:Highest number of patients undergoing elective non-cardiac surgery belonged to the younger age group. General surgery had the highest number of patients 45.3%, followed by Orthopaedics (36%), Gynaecology (18.7%). In view of surgery done by 3 above-mentioned surgical branches, there was not much difference in the rate of risk ofcardiovascular events. Diabetes mellitus, hypertension, and cardiac diseases were found as frequent risk factors (44 (29.3%), 52 (34.6%), 26 (17.3%) respectively.) Postoperative cardiovascular complication rate was most commonly seen in cardiac diseases, which were 8 (30.7%) patients. The incidence of perioperative cardiac complication in our study was 8.7% with 4% mortality. Conclusion:The incidence of complication was highest in patients undergoing high risk surgeries like intraperitoneal surgery. The RCRI classification was a good preoperative tool for risk stratification of patients undergoing non-cardiac surgery.

Polaron hopping in some biomolecular solids and their charge transfer complexes.

The solid state spectroscopy of charge transfer complexes of biomolecules such as fatty acids, tripalmitin, lysozyme. folic acid, beta-carotene, cytochrome c, valinomycin and gramicidin has been carried out. The absorption coefficient is related with electronic conductivity. A half-power beta density is found common among these macromolecular solids, indicating photon-induced polaron hopping or hopping of a charge carrier between two branches of a polariton. Band gap vs full width at half-maximum of the mid-IR peak also reveals a linear relation.