main non clinical risk factors of major thalassemia in Fars provin

Thalassemia major is one of the most common genetic blood disorders that passes from parents to children. Since Fars province is one of the most common locations of thalassemia in our country. It seems that the present study can be helpful by identifying main non-clinical factors of the disease. This cross sectional study was done on registered data of less than 12 year old major thalassemia patients in Fars province by census method in 1997-2010. Underlying causes of thalassemia are divided into three groups: S[1] cases due to hardware problems, S[2] cases due to parents carelessness without having a history, and S[3] patients born to parents who married when genetic tests were not routine. Data were analyzed by using SPSS 16 and ANOVA tests. Analysis showed that S[1] with 48 persons [15.38%] with the mean age of 5.6 +/- 3.2, S[2] with 71 persons [22.75%] with the mean age of 6.8 +/- 1.2, and S[3] with 193 person [61.85%] with the mean age of 8.8 +/- 3.30 were the main groups of thalassemia .The least incidence rate was 0.13 per 10000 in 2010. With identifying the main underlying causes of major thalassemia regardless of its main cause which is herediatry from parents, considering levels and different consequences of these causes, and high efficiency of genetic tests before marriage, effective steps can be taken to reduce health-social and economic problems of thalassemia

[Ultra analysis of prevalence of osteoporosis in Iranian women "a systematic review and meta-analysis"]

There are many descriptive studies on osteoporosis in Iran, mostly assessing the prevalence of the disease and its associations with various risk factors. In order to gain a better insight into the epidemiology of osteoporosis in Iran and its heterogeneity around the country, we systematically reviewed all the studies available and analyzed their findings using meta-analysis methods. All published papers in Iranian and international journals, final reports of research projects, papers presented in relevant congresses, and all dissertations of medical students were reviewed using standard methods and sensitive keywords. After Quality Assessment the main results of studies published during 2000-2008, which met the eligibility criteria, were extracted and Combined with the Random Effect Model, and were entered into metaanalysis. In 21 primary, eligible studies, minimum and maximim prevalence rates in the femur region were 1.5 and 43 respectively and in the Spinal Region these values were 3.2 and 51.3, respectively. The prevalence of osteoporosis in the femur using the Random Effect Model in Iranian Women was 18.9 CI [15- 22.7] and in the Spinal reqion was 18.91 CI [14.6- 23.2] in metaregrresion analysis, with place and sample size as the main heterogenous factors [p<0.01]. Osteoporosis, an important health challenge, increases with age and changes in life style. The prevalence of osteoporosis in Iran, compared to other countries, was lower

comparison of prevalence of diabete and hypertension between rural areas of Fars and rural area of EMRO region

Since monitoring and evaluation of diabetes and hypertension in individuals/the population greatly contribute to improving both clinical care and following identification of disease in the region and even the country, and to manage prevent and control diabetes and hypertension and their risk factors, the goal of this study was to compare disease status in rural areas of Fars province and rural areas of the EMRO region. The current study is a descriptive-analytic cross sectional one that has been conducted in 2008 by randomized cluster sampling, based on data obtained from an extensive provincial screening plan for adults aged over 30 years in rural areas of Fars province. Based on these data, the prevalence of diabetes, hypertension and their risk factors were calculated and the relationship between diabetes and hypertension was determined by risk factors including age, sex, family history, and Ml using Chi square and t-test and SPSS software version 17 and Minitab version, prevalences in 15 is rural areas were compared with the ones in EMRO region countries. The prevalence of hypertension and diabetes rural areas of Fars province were calculated to be 21.8% and 11.14% respectively as compared with rural areas of EMRO region countries.The prevalence of diabetes was also lower on the average and the prevalence of obesity [BMI>30], was less than other countries in the region and Iran. In general, although, the prevalence obtained in this study was lower than other regional countries, raising a wareness in high rish groups affected public commitment to basic information transmitting to high risk classes of the society should be taken into account and commitment by the health system administration and the government to sustain monitoring of health, to ensure curtailing the burden of diabetes and hypertension and associated risk factors among countries of the region