RESUMO
Osteoporosis is a major health problem for postmenopatisal women and use of dual x-ray absorptiometry [DXA] is standard diagnostic method. But due to the cost, it is not economical to use for screening of all postmenopausal women, thus, the aim of this study was to evaluate performance of Osteoporosis Risk Assessment Instrument [ORAI] as a tool for screening of Osteoporosis among Iranian postmenopausal women. In this study data was collected from a bone densitometry centre. The Osteoporosis risk was evaluated for 341 postmenopausal women [age > 45 years] without consider secondary cause of Osteoporosis. The results were compared with their bone mineral density. From 341 postmenopausal women, 20.8% were showed osteoporotic and 39.6% had low bone mineral density in one or both studied area by DXA. To assess Osteoporosis of low bone mass, ORAI was shown a sensitivity of 70.9% and specificity of 66.9% respectively. The ORAI was adequate sensitivity to evaluate Iranian postmenopausal women. This test could be used as screen test to determinate low bone mineral density to referral of women
RESUMO
The correct interpretation of bone mineral density [BMD] measurement by dual energy x ray absorptiometry [DEXA] requires a population specific reference range. We collected data on age 20-35 years to obtain reference values of BMD for Isfahani women in order to make a population specific diagnosis of osteoporosis. In 660 healthy Isfahani women Volunteers [20-35 years] without illness, use of drugs or predisposing conditions to osteoporosis, the BMD [gr/cm 2] of lumbar spine and non-dominant femur was measured by lunar DPX -IQ machine. The mean BMD and its standard deviations at each site were calculated and compared with normative data from Caucasian US/North European women. No significant differences were detected between them. Bone mineral density measurements of these 660 healthy Isfahani women can serve as a reference guide for the diagnosis of osteoporosis in Isfahani women