RESUMO
Introduction: Despite the dramatic improvement in the short-term outcome of kidney transplantation 30% or more of patients will lose their allograft before the fifth transplant anniversary. Second renal allograft survival rates are lower than those of primary allograft in many studies. This study is carried out to identify risk factors associated with decreased second regraft survival
Material and Method: from 1989 through 2002, 650 primary and 37 first repeat transplans were performed on Imam Reza hospital. Graft survival rates for primary transplants at 12, 36 and 60 months after transplantation were 93%, 89%, 76% respectively, compared with 87%, 79%, 68%, for transplants at the same time periods
Result: we observed no effect of recipient age and sex, time interval between primary graft loss and second transplantation or allograft nephrectomy on outcome for patients who had undergone retransplantation or allograft nephrectomy on outcome for patients who had undergone retransplantation. Causes of the first graft failure were analyzed. Regraft failure is more common in patients who lost their first graft because of acute rejection than patients who had chronic rejection
Conclusion: The result showed a significant relationship between primary allograft survival, PRA and PPRA level and retransplant outcome