1.
Indian J Exp Biol
;
1991 Mar; 29(3): 230-2
Artigo
em Inglês
| IMSEAR
| ID: sea-57425
RESUMO
Emodin, an anthraquinone derivative, isolated from the whole plant of R. triquerta, in 15 mg/kg dose (ip) exhibited anti-inflammatory activity against carrageenin-induced pedal inflammation in rats. In the same dosage it also showed antiulcer activity against 4 hr pylorus-ligated, aspirin and immobilization stress-induced gastric ulcers in rats. It decreased acid and pepsin output and augmented mucus secretion in terms of total carbohydrate: protein ratio in the gastric juice of aspirin treated pylorus-ligated rats, indicating that the antiulcerogenic effect of emodin may be due to its effect on gastric secretion.
Assuntos
Animais , Anti-Inflamatórios não Esteroides , Antiulcerosos , Emodina/isolamento & purificação , Feminino , Suco Gástrico/efeitos dos fármacos , Inflamação/prevenção & controle , Masculino , Ratos , Úlcera/prevenção & controle
2.
Indian J Exp Biol
;
1988 Feb; 26(2): 121-4
Artigo
em Inglês
| IMSEAR
| ID: sea-61647
3.
Artigo
em Inglês
| IMSEAR
| ID: sea-22147